Results 91 to 100 of about 1,295,490 (295)

Chromosomal integrity after UV irradiation requires FANCD2-mediated repair of double strand breaks [PDF]

open access: yes, 2016
Fanconi Anemia (FA) is a rare autosomal recessive disorder characterized by hypersensitivity to inter-strand crosslinks (ICLs). FANCD2, a central factor of the FA pathway, is essential for the repair of double strand breaks (DSBs) generated during fork ...
Bocco, Jose Luis   +7 more
core   +3 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Survival of Lactobacillus helveticus CNRZ32 in spray dried functional yogurt powder during processing and storage

open access: yesJournal of the Saudi Society of Agricultural Sciences, 2020
Fresh set-yogurt fortified with functional lactic acid bacteria (Lactobacillus helveticus CNRZ32) was manufactured in two sets, plain and supplemented with butter milk powder. All samples were spray dried at two specific inlet air temperatures 150 °C and
Hoda S. El-Sayed   +2 more
doaj   +1 more source

Neurogenesis Drives Stimulus Decorrelation in a Model of the Olfactory Bulb [PDF]

open access: yes, 2012
The reshaping and decorrelation of similar activity patterns by neuronal networks can enhance their discriminability, storage, and retrieval. How can such networks learn to decorrelate new complex patterns, as they arise in the olfactory system?
A Arevian   +81 more
core   +6 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Integrated genomic analysis of mitochondrial RNA processing in human cancers

open access: yesGenome Medicine, 2017
Background The mitochondrial genome is transcribed as continuous polycistrons of RNA containing multiple genes. As a consequence, post-transcriptional events are critical for the regulation of gene expression and therefore all aspects of mitochondrial ...
Youssef Idaghdour, Alan Hodgkinson
doaj   +1 more source

Screening the Cancer Genome Atlas Database for Genes of Prognostic Value in Acute Myeloid Leukemia

open access: yesFrontiers in Oncology, 2020
Object: To identify genes of prognostic value which associated with tumor microenvironment (TME) in acute myeloid leukemia (AML).Methods and Materials: Level 3 AML patients gene transcriptome profiles were downloaded from The Cancer Genome Atlas (TCGA ...
Jie Ni   +7 more
doaj   +1 more source

Management of plant health risks associated with processing of plant-based wastes: A review [PDF]

open access: yes, 2009
The rise in international trade of plants and plant products has increased the risk of introduction and spread of plant pathogens and pests. In addition, new risks are arising from the implementation of more environmentally friendly methods of ...
Budge, G. E.   +4 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Survival of seed-coated microbial biocontrol agents during seed storage

open access: yesBiological Control
Biological control of seedborne pathogens and soilborne seedling pathogens through antagonists applied on seeds is an alternative to chemical seed treatments.
Jürgen Köhl   +9 more
doaj   +1 more source

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