Results 121 to 130 of about 60,299 (235)
Multidrug resistance of non-adherent cancer cells [PDF]
, 2010 Metastases are the cause of 90% of human cancer deaths. Cancer in _situ_ can usually be effectively removed by surgery. Once cancer cells disseminate from the original site and start to circulate in blood, lymph, or other body fluids, the disease becomes
Guangming Liu +2 more
core +1 more source
Paeonol Inhibits Cell Growth by Inducing Ferroptosis in Human Glioma Cells
Pharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.ABSTRACT Paeonol (PAE), a phenolic phytochemical derived from traditional Chinese medicinal plants, exhibits multifaceted pharmacological properties including demonstrated antitumor efficacy against hepatic, gastric, and breast carcinomas. However, its therapeutic potential in glioma remains unexplored.
Xin Li +8 more
wiley +1 more source
Exosomal survivin facilitates vesicle internalization
Oncotarget, 2018 Survivin, a member of the inhibitor of apoptosis (IAP) protein family plays a significant role in cell fate and function. It is significantly overexpressed in tumor cells and has been identified in most cancer cell types. A novel extracellular population has recently been identified and its function is still unknown. Emerging evidence continues to shed
Gonda, Amber +6 more
openaire +3 more sources
Deciphering the Transcriptomic Signatures of Aging Across Organs in Mice
Aging Cell, Volume 25, Issue 2, February 2026.Comprehensive transcriptomic profiling of eight mouse organs across six ages reveals how aging reshapes biological processes. Trajectory and network analyses distinguish shared and organ‐specific signatures, charting the molecular landscape of systemic aging.
Sarah Morsy +9 more
wiley +1 more source
Survivin induces defects in apoptosis in eosinophils in intestine with food allergy
Innate Immunity, 2019 Survivin is an anti-apoptosis protein that may be associated with the development of eosinophilia; the latter is associated with the pathogenesis of many immune disorders.
Han Gao +11 more
doaj +1 more source
Therapeutic Challenge with a CDK 4/6 Inhibitor Induces an RB-Dependent SMAC-Mediated Apoptotic Response in Non-Small Cell Lung Cancer. [PDF]
, 2018 Purpose: The retinoblastoma tumor suppressor (RB), a key regulator of cell-cycle progression and proliferation, is functionally suppressed in up to 50% of non-small cell lung cancer (NSCLC).
Addya, Sankar +14 more
core +1 more source
Prospects for non-immunological molecular therapeutics in melanoma [PDF]
, 2010 In 2006 there were 60,000 new cases of cutaneous melanoma in the European Union and 13,000 deaths (www.europeancancerleagues.org). Currently available systemic treatment options for metastatic melanoma, including both cytotoxic and immunologic therapies,
Crown, John +4 more
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Cell Communication and SignalingBackground Bivalent regions of chromatin (BvCR) are characterized by trimethylated lysine 4 (H3K4me3) and lysine 27 on histone H3 (H3K27me3) deposition which aid gene expression control during cell differentiation.
Venkataragavan Chandrasekaran +9 more
doaj +1 more source
Survivin in brain tumors: an attractive target for immunotherapy [PDF]
, 2018 Summary: Survivin, a member of the inhibitor of apoptosis proteins gene family, was recently shown to be expressed by tumors originating from different cell lineages.
Belkouch, Marie-Claude +5 more
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