Results 111 to 120 of about 41,070 (225)

Heat Shock Proteins in Cancer: Mechanisms and Therapeutic Targeting

MedComm, Volume 7, Issue 9, September 2026.
This review illustrates heat shock proteins (HSPs) as central regulators of cancer metabolic reprogramming. By stabilizing key metabolic enzymes and coordinating glycolysis, oxidative phosphorylation, redox homeostasis, and stress adaptation, HSPs support tumor growth, metastasis, and therapeutic resistance. Targeting HSP networks may therefore provide
Sheng Ma, Chen‐Qian Liu, Si‐Yang Ma, Shao‐Gang Wang, Qi‐Dong Xia, Meng‐Yao Xu   +5 more
wiley   +1 more source

Molecular Mechanisms and Therapeutic Applications of Extracellular Vesicles in Remodeling of the Skin Cancer Niche

Nano Select, Volume 7, Issue 9, September 2026.
Extracellular vesicles at the nexus of skin cancer progression and precision therapy. EVs orchestrate tumor microenvironment remodeling through cargo‐mediated intercellular communication, immune modulation, angiogenesis, and extracellular matrix reorganization, while also emerging as next‐generation platforms for targeted drug delivery, biomarker ...
Megha Kotian, Maria Nison, Deepanjan Datta, Soniya Kumbham, Namdev Dhas, Praveen Halagali, Vasudev R Pai, Vamshi Krishna Tippavajhala   +7 more
wiley   +1 more source

Localization and upregulation of survivin in cancer health disparities: a clinical perspective

, 2015
Salma Khan,1,2 Heather Ferguson Bennit,1,2 Malyn May Asuncion Valenzuela,1,2 David Turay,1,3 Carlos J Diaz Osterman,1,2 Ron B Moyron,1,2 Grace E Esebanmen,1,2 Arjun Ashok,1,2 Nathan R Wall1,2 1Department of Biochemistry, 2Center for Health Disparities ...
Asuncion Valenzuela MM, Moyron RB, Ferguson Bennit H, Turay D, Esebanmen GE, Ashok A, Wall NR, Diaz Osterman CJ, Khan S   +8 more
core  

Delafloxacin suppresses DEPDC1 expression and induces G2/M arrest in non‐small cell lung cancer cells: A drug repurposing study

Smart Molecules, Volume 4, Issue 3, September 2026.
This study presents Delafloxacin repurposed as a DEPDC1‐targeting therapeutic aiming to suppress lung cancer progression. It highlights a novel strategy for lung cancer treatment with potential clinical applications. Abstract Emerging evidence highlights the oncogenic role of the Dishevelled, Egl‐10, and Pleckstrin domains containing 1 (DEPDC1) gene in
Noman Ali, Farishta Shafiq, Mishal Iftikhar, Muhammad Shahzad Zafar, Muhammad Shoaib   +4 more
wiley   +1 more source

Aurora B Kinase Exists in a Complex with Survivin and INCENP and Its Kinase Activity Is Stimulated by

, 2002
Aurora B regulates chromosome segregation and cytokinesis and is the first protein to be implicated as a regulator of bipolar attachment of spindle microtubules to kinetochores.
Mark L. Mcclel, Shannon E. Powers, Jian Kuang, Weijie Lan, Survivin Binding, P. Todd Stukenberg, Margaret A. Bolton   +6 more
core  

Therapeutic Effects of Matricaria chamomilla Extract in an Immunosuppressed Mouse Model of Cryptosporidiosis

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Chamomile (Matricaria chamomilla) extract significantly reduced oocyst shedding and intestinal lesions in immunosuppressed mice infected with Cryptosporidium parvum, while enhancing antioxidant defences (GPx, TAC). These findings suggest chamomile as a promising phytotherapeutic agent for cryptosporidiosis. ABSTRACT Background Cryptosporidiosis, caused
Kousha Kiani, Mohammad Hashemnia, Farid Rezaei, Hadi Cheraghi   +3 more
wiley   +1 more source

Anti-HER2 functionalized graphene oxide as survivin-siRNA delivery carrier inhibits breast carcinoma growth in vitro and in vivo

, 2018
Xiaoli Wang,1–3 Qi Sun,1–3 Chunying Cui,1–3 Jing Li,1–3 Yifan Wang1–3 1Department of Pharmaceutics, School of Pharmaceutical Sciences, Capital Medical University, Beijing, China; 2Beijing Area Major Laboratory of Peptide ...
Li J, Sun Q, Wang X, Cui C, Wang Y
core  

Do the survivin (BIRC5) splice variants modulate or add to the prognostic value of total survivin in breast cancer?

, 2006
Contains fulltext : 51297.pdf (Publisher’s version ) (Open Access)BACKGROUND: A total of 4 additional splice variants (survivin-DeltaEx3, survivin 2alpha, survivin-2B, and survivin-3B) have been described for survivin [baculoviral IAP ...
Span, P.N., Kok, J.B. de, Tjan-Heijnen, V.C., Sweep, C.G.J., Heuvel, J.J.T.M., Foekens, J.A.   +5 more
core   +1 more source

Survivin' Cancer [PDF]

Cancer Biology & Therapy, 2004
openaire   +2 more sources

The role of survivin in autophagy [PDF]

Survivin is a highly conserved protein with important roles in cell death and mitosis; deletion of the survivin gene is embryonically lethal. It is highly expressed in most cancers, making it a promising target for cancer therapy. Autophagy, an important
Humphry, Nicola
core   +3 more sources