Results 121 to 130 of about 59,883 (231)
Survivin--a universal tumor antigen.
Tumor-associated antigens recognized by cellular effectors of the immune system are potential targets for antigen-specific cancer immunotherapy. These antigens are classified as tissue (melanocyte)-specific proteins, cancer-testis antigens (proteins expressed in normal testis and various cancers), tumor-specific peptides derived from mutations in tumor
Andersen, M.H., thor Straten, P.
openaire +3 more sources
To study survivin gene expression in APL cells and to explore its correlation with clinical manifestations. PML/RARα and survivin mRNA expression were analysed using RT-PCR.
Jun Xue, Xiao-Jing Xie, Mao-Fang Lin
doaj +1 more source
Multidrug resistance of non-adherent cancer cells [PDF]
Metastases are the cause of 90% of human cancer deaths. Cancer in _situ_ can usually be effectively removed by surgery. Once cancer cells disseminate from the original site and start to circulate in blood, lymph, or other body fluids, the disease becomes
Guangming Liu +2 more
core +1 more source
Exosomal survivin facilitates vesicle internalization
Survivin, a member of the inhibitor of apoptosis (IAP) protein family plays a significant role in cell fate and function. It is significantly overexpressed in tumor cells and has been identified in most cancer cell types. A novel extracellular population has recently been identified and its function is still unknown. Emerging evidence continues to shed
Gonda, Amber +6 more
openaire +3 more sources
Survivin induces defects in apoptosis in eosinophils in intestine with food allergy
Survivin is an anti-apoptosis protein that may be associated with the development of eosinophilia; the latter is associated with the pathogenesis of many immune disorders.
Han Gao +11 more
doaj +1 more source
PI3K inhibition enhances the anti-tumor effect of eribulin in triple negative breast cancer [PDF]
Loss of the tumor suppressor phosphatase and tensin homolog (PTEN) is commonly observed in triple negative breast cancer (TNBC), leading to activation of the phosphoinositide 3-kinase (PI3K) signaling to promote tumor cell growth and chemotherapy ...
Guo, Zhanfang +3 more
core +1 more source
Background Bivalent regions of chromatin (BvCR) are characterized by trimethylated lysine 4 (H3K4me3) and lysine 27 on histone H3 (H3K27me3) deposition which aid gene expression control during cell differentiation.
Venkataragavan Chandrasekaran +9 more
doaj +1 more source
Survivin in brain tumors: an attractive target for immunotherapy [PDF]
Summary: Survivin, a member of the inhibitor of apoptosis proteins gene family, was recently shown to be expressed by tumors originating from different cell lineages.
Belkouch, Marie-Claude +5 more
core
Introduction: Survivin is a new member of the Inhibitor Apotosis Protein family (IAP) which plays an important role in the regulation of both cell cycle and apoptosis.
E Babaei +4 more
doaj

