Targeting and Suppression of Survivin in Cancer Cells Based on the Interaction of Cell Surface Vimentin with <i>N</i>‑Acetylglucosamine-Bearing Polymers. [PDF]
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Tumor-specific immune responses and biomarkers in pediatric patients with high-risk Hodgkin lymphoma. [PDF]
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Synergistic Anticancer Effects of Metformin and Doxorubicin in Ovarian Cancer Cells Through Dual Apoptotic Pathway Activation and Oxidative Stress Enhancement. [PDF]
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Therapeutic efficacy of oncolytic adenovirus YSCH-01 in osteosarcoma evaluated in PDX and CDX mouse models. [PDF]
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Dual inhibition of MAPK and TORC1 signaling retards development of radiation resistance in pediatric BRAFV600E glioma models. [PDF]
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[Expression of Concern] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells. [PDF]
Tang C, Hahm E, Bae S, Kang JS, Lee WJ.
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Survivin is a unique member of the inhibitor-of-apoptosis family. Survivin plays a role in the proliferation and survival of normal hematopoietic cells. Survivin expression is aberrantly enhanced in most cancers and hematopoietic malignancies. Survivin is an attractive therapeutic target, and various approaches to targeting survivin have been tested in
Xiu Li, Cong, Zhong Chao, Han
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Abstract Readers are encouraged to write letters to the editor concerning articles that have been published in Gastroenterology. Short, general comments are also considered, but use of the Correspondence section for publication of original data in preliminary form is not encouraged.
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Survivin in autoimmune diseases
Autoimmunity Reviews, 2017Survivin is a protein functionally important for cell division, apoptosis, and possibly, for micro-RNA biogenesis. It is an established marker of malignant cell transformation. In non-malignant conditions, the unique properties of survivin make it indispensable for homeostasis of the immune system.
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