Results 191 to 200 of about 60,299 (235)

The hydroxamate based HDAC inhibitor WMJ-J-09 induces colorectal cancer cell death by targeting tubulin and downregulating survivin. [PDF]

Sci Rep
Huang YH, Huang YM, Huang WJ, Yu MC, Chuang CH, Hsu YF, Chen HC, Chen LC, Huang SW, Hsu MJ.   +9 more
europepmc   +1 more source

Effect of human survivin-2B-specific cytotoxic CD8+ T lymphocytes on CD44+/- HSC-2 and HSC-3 oral cancer cells. [PDF]

Eur J Oral Sci
Miyamoto S, Osaki A, Murai A, Hirohashi Y, Sasaki T, Ogi K, Tokura TA, Kanaseki T, Tsukahara T, Kina S, Torigoe T, Miyazaki A.   +11 more
europepmc   +1 more source

Survivin at a glance [PDF]

Journal of Cell Science, 2019
ABSTRACT Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upregulated in most, if not all cancers; consequently, it has received significant attention as a potential ...
Sally P Wheatley, Dario C Altieri
exaly   +4 more sources

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Survivin and Leukemia

International Journal of Hematology, 2004
Survivin is a unique member of the inhibitor-of-apoptosis family. Survivin plays a role in the proliferation and survival of normal hematopoietic cells. Survivin expression is aberrantly enhanced in most cancers and hematopoietic malignancies. Survivin is an attractive therapeutic target, and various approaches to targeting survivin have been tested in
Xiu Li, Cong, Zhong Chao, Han
openaire   +2 more sources

Targeting survivin in cancer [PDF]

Cancer Letters, 2013
With almost 4000 citations in Medline in a little over 10 years, survivin has certainly kept scores of investigators busy worldwide. Tangible progress has been made in revealing the multiple functions of survivin, uncovering their wirings as integrated cellular networks, and mapping their exploitation in virtually every human tumor, in vivo ...
Dario C Altieri
exaly   +3 more sources

Survivin in liver

Gastroenterology, 2003
Abstract Readers are encouraged to write letters to the editor concerning articles that have been published in Gastroenterology. Short, general comments are also considered, but use of the Correspondence section for publication of original data in preliminary form is not encouraged.
Katsuya, Shiraki, Takeshi, Nakano, Hisashi, Hisatomi   +2 more
openaire   +2 more sources

Survivin in autoimmune diseases

Autoimmunity Reviews, 2017
Survivin is a protein functionally important for cell division, apoptosis, and possibly, for micro-RNA biogenesis. It is an established marker of malignant cell transformation. In non-malignant conditions, the unique properties of survivin make it indispensable for homeostasis of the immune system.
G, Gravina, C, Wasén, M J, Garcia-Bonete, M, Turkkila, M C, Erlandsson, S, Töyrä Silfverswärd, M, Brisslert, R, Pullerits, K M, Andersson, G, Katona, M I, Bokarewa   +10 more
openaire   +2 more sources

Differential expression of survivin and its splice variants, survivin-ΔEx3 and survivin-2B, in bladder cancer

Cancer Detection and Prevention, 2009
Survivin, an inhibitor of apoptosis protein (IAP), has been regarded as a valuable tumor marker for diagnosis and prognosis of bladder cancer. Recently, three splice variants of the gene with different anti-apoptotic activities have been reported. However, there is no data on the expression and potential causative roles of these transcripts in bladder ...
Yaser, Atlasi, Seyed Javad, Mowla, Seyed Amir-Mohsen, Ziaee   +2 more
openaire   +2 more sources

Survivin expression in ganglioglioma

Journal of Neuro-Oncology, 2005
Gangliogliomas are unusual central nervous system (CNS) neoplasms occurring mainly in children and young adults and inducing chronic pharmacoresistant epilepsy. These are usually well differentiated neuroepithelial tumors composed of neurons in association with neoplastic glial cells. Gangliogliomas present with favorable outcome.
Audrey, Rousseau, Michèle, Kujas, Anne-Marie, Bergemer-Fouquet, Rémy, van Effenterre, Jean-Jacques, Hauw   +4 more
openaire   +2 more sources

Survivin and gynaecological tumours

Pathology - Research and Practice, 2017
Survivin is the smallest member of the inhibitors of apoptosis (IAP) family. However, participation in inhibition of apoptosis is not the only function of this molecule. Survivin can also affect the proper process of mitosis and even promoting of angiogenesis or DNA repair.
Dušan, Braný, Dana, Dvorská, Pavol, Slávik, Richard, Školka, Marián, Adamkov   +4 more
openaire   +2 more sources