Results 181 to 190 of about 41,070 (225)

Survivin, Survivin-2B, and Survivin-deItaEx3 expression in medulloblastoma: biologic markers of tumour morphology and clinical outcome [PDF]

open access: yesBritish Journal of Cancer, 2005
Survivin is an apoptotic inhibitor that is expressed at high levels in a variety of malignancies. Survivin has four known alternative splice forms (Survivin, Survivin-2B, Survivin-deltaEx3, and Survivin-3B), and the recent literature suggests that these splice variants have unique functions and subcellular localisation patterns.
Venktesh Singh
exaly   +3 more sources
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Survivin and Leukemia

International Journal of Hematology, 2004
Survivin is a unique member of the inhibitor-of-apoptosis family. Survivin plays a role in the proliferation and survival of normal hematopoietic cells. Survivin expression is aberrantly enhanced in most cancers and hematopoietic malignancies. Survivin is an attractive therapeutic target, and various approaches to targeting survivin have been tested in
Xiu Li, Cong, Zhong Chao, Han
openaire   +2 more sources

Survivin in liver

Gastroenterology, 2003
Abstract Readers are encouraged to write letters to the editor concerning articles that have been published in Gastroenterology. Short, general comments are also considered, but use of the Correspondence section for publication of original data in preliminary form is not encouraged.
Katsuya, Shiraki   +2 more
openaire   +2 more sources

Targeting survivin in cancer [PDF]

open access: yesCancer Letters, 2013
With almost 4000 citations in Medline in a little over 10 years, survivin has certainly kept scores of investigators busy worldwide. Tangible progress has been made in revealing the multiple functions of survivin, uncovering their wirings as integrated cellular networks, and mapping their exploitation in virtually every human tumor, in vivo ...
Dario C Altieri
exaly   +3 more sources

Differential expression of survivin and its splice variants, survivin-ΔEx3 and survivin-2B, in bladder cancer

Cancer Detection and Prevention, 2009
Survivin, an inhibitor of apoptosis protein (IAP), has been regarded as a valuable tumor marker for diagnosis and prognosis of bladder cancer. Recently, three splice variants of the gene with different anti-apoptotic activities have been reported. However, there is no data on the expression and potential causative roles of these transcripts in bladder ...
Yaser, Atlasi   +2 more
openaire   +2 more sources

Survivin expression in oral squamous cell carcinoma

open access: yesBritish Journal of Cancer, 2003
A series of 110 cases of oral squamous cell carcinoma (SCC) together with six lymph node and one distant metastatic lesions was analysed for expression of survivin, a recent apoptosis inhibitor, by immunohistochemistry and Western blotting.
Fabrizio Ferrari   +2 more
exaly   +2 more sources

Survivin and gynaecological tumours

Pathology - Research and Practice, 2017
Survivin is the smallest member of the inhibitors of apoptosis (IAP) family. However, participation in inhibition of apoptosis is not the only function of this molecule. Survivin can also affect the proper process of mitosis and even promoting of angiogenesis or DNA repair.
Dušan, Braný   +4 more
openaire   +2 more sources

Survivin expression in ganglioglioma

Journal of Neuro-Oncology, 2005
Gangliogliomas are unusual central nervous system (CNS) neoplasms occurring mainly in children and young adults and inducing chronic pharmacoresistant epilepsy. These are usually well differentiated neuroepithelial tumors composed of neurons in association with neoplastic glial cells. Gangliogliomas present with favorable outcome.
Audrey, Rousseau   +4 more
openaire   +2 more sources

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