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High expression of survivin and its splice variants survivin ΔEx3 and survivin 2 B in oral cancers
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2015We have previously reported inactivation of p53 in 46% of Indian patients with oral cancer. Survivin, a p53 target gene and an inhibitor of apoptosis protein (IAP), is overexpressed in several cancers, including oral cancers. Studies assessing the role of survivin and its splice variants in oral cancers are, however, rare.The expression of 6 survivin ...
Rupa, Mishra +4 more
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Survivin in survival of hepatocellular carcinoma
Cancer Letters, 2016Survivin is an anti-apoptotic protein belonging to the inhibitor of apoptosis protein (IAP) family. It is involved in the regulation of important physiological and pathological processes in cells and functions to inhibit cell apoptosis and promote cell proliferation. Normally and terminally differentiated tissues are nearly negative for survivin.
Changqing Su
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Survivin and apoptosis control
2003Survivin is a member of the inhibitor of apoptosis (TAP) gene family that exhibits differential expression in nearly all human cancers but not in most normal tissues. Recent progress identified a multifunctional survivin pathway positioned at the interface between mitotic progression and apoptosis inhibition, and required to preserve viability of ...
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Role of survivin and its splice variants in tumorigenesis
British Journal of Cancer, 2004Fengzhi Li
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Differential subcellular localization of functionally divergent survivin splice variants
Cell Death and Differentiation, 2002C D Gerharz, C Mahotka, H E Gabbert
exaly