Results 81 to 90 of about 506,209 (297)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Baseline right ventricular end-diastolic volume index (RVEDVI) in survivors and non-survivors

, 2011
Baseline RVEDVI was similar in both survivors and non-survivors. Change in RVEDVI from baseline at the point of maximum cardiac index response. The mean increase in RVEDVI was significantly greater in survivors than non-survivors (p = 0.0047).
Eugene Bunnell (51074), Barry Milcarek (51076), Joseph E Parrillo (51077), Anand Kumar (24122), Amjad Ali (51075), Elizabeth Schupp (51073)   +5 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

The differences in the psychological impact of trauma between female rape and non-sexual assault survivors [PDF]

, 2008
Includes bibliographical references (leaves 155-177).International research suggests that rape impacts more negatively on the mental health of rape survivors than non-sexual assault.
Edross, Sadia
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Feasibility test of a UK-scalable electronic system for regular collection of patient-reported outcome measures and linkage with clinical cancer registry data: The electronic Patient-reported Outcomes from Cancer Survivors (ePOCS) system [PDF]

, 2011
Background Cancer survivors can face significant physical and psychosocial challenges; there is a need to identify and predict which survivors experience what sorts of difficulties.
Velikova, G, Amy Downing, Jones Helen, Velikova Galina, Wright Penny, Alex Newsham, Newsham, A, Penny Wright, David Forman, Downing, A, Forman David, Wright, EP, Helen Jones, Laura Ashley, Newsham Alex, Downing Amy, Ashley, L, Ashley Laura, Forman, D, Julia Brown, Brown Julia, Galina Velikova, Brown, J, Jones, H, Wright, P   +24 more
core   +2 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

The psychological impact of rape : a long longitudinal study of adult female survivors in the Western Cape, South Africa [PDF]

, 2013
Includes bibliographical references.There is a broad body of research which suggests that rape is highly pathogenic, most commonly described in terms of Post Traumatic Stress Disorder (PTSD).
Maw, Anastasia
core   +1 more source

“And Then One Day, Me and My Husband, We Learned How to Cross the Street”: Hazara Women’s Experiences in Sydney and Yearnings for ‘Home’

Genealogy
As numbers of displaced people throughout the world steadily increase with the rise in global conflicts, many Western nations, including Australia, increasingly thwart asylum-seeking and place harsh restrictions on entry.
Rimple Mehta, Linda Briskman, Michel Edenborough, Fran Gale, Samantha Tom Cherian, Mohammad Arif Nabizadah, Jasmina Bajraktarevic-Hayward, Asma Naurozi   +7 more
doaj   +1 more source