Results 41 to 50 of about 4,800,471 (257)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Quantitative landslide susceptibility assessment of the Waikato region using GIS [PDF]

open access: yes, 2010
Areas that have experienced landslide events in the past and the conditioning factors present at these sites can be used to identify areas of the same or similar susceptibility.
Schicker, Renee Deborah
core  

Autobac I procedure to assess susceptibility to Cefaclor [PDF]

open access: yesJournal of Clinical Microbiology, 1980
Agar dilution and Autobac I tests were performed to compare the susceptibility of 1,000 bacterial isolates to cefaclor and cephalothin. The standard Autobac methodology will correctly predict resistance to cefaclor. The test methodology seems to influence in vitro results, since more strains of gram-negative bacteria were susceptible to cefaclor by the
D, Gröschel, K, Mills, R L, Hopfer
openaire   +2 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Strategic assessment of bridge susceptibility to scour

open access: yesReliability Engineering & System Safety
Scour-induced failures of bridges pose a global challenge, leading to significant economic and service losses. Compounded by infrequent inspections and inadequate consideration of hydro-geological factors in current scour risk assessments, this issue is particularly pressing in the context of climate change and associated hazards.
Moustafa Naiem Abdel-Mooty   +6 more
openaire   +3 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Changing Assessment Practice: Process, Principles and Standards [PDF]

open access: yes, 2008
This is a brief account of what has been learned during the Analysis and Review of Innovations in Assessment (ARIA) project about how changes in assessment practice may be brought about most eff ectively.
Gardner, John   +3 more
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Formation conditions and susceptibility assessment of karst collapses in the northern hilly area of Guangzhou City

open access: yesZhongguo dizhi zaihai yu fangzhi xuebao
Karst collapse is one of the main geological disasters in the northern hilly area of Guangzhou City, posing practical threats to public safety and affecting harmonious living conditions, thereby constraining local rural revitalization and development ...
Zhongzhong WANG   +3 more
doaj   +1 more source

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