Results 61 to 70 of about 4,800,471 (257)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Classification optimization of geological hazard susceptibility evaluation factors based on AIFFC algorithm

Zhongguo dizhi zaihai yu fangzhi xuebao
This paper addresses the issue of uncertainty in the grading of geological hazard susceptibility evaluation factors and introduces the adaptive expansion factor fuzzy coverage grading method (AIFFC) to optimize the grading of geological hazard ...
Bin CHEN, Yingyi LI, Lianzhi ZHANG, Tianqiang QU, Na WEI, Ning LIU, Chunlin HUANG   +6 more
doaj   +1 more source

Assessment of the susceptibility of lactic acid bacteria to biocides [PDF]

International Journal of Food Microbiology, 2013
Biocides are antimicrobial compounds that are widely used in the food industry and medical environments. In this study, we determined the Minimum Inhibitory Concentrations (MICs) by the microdilution method of four different biocides for a large collection of LAB of different origins.
S. Arioli, M. Elli, G. Ricci, D. Mora
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Development characteristics and risk assessment of geological hazards along the Lanzhou-Chengdu-Chongqing refined oil pipeline based on machine learning

Zhongguo dizhi zaihai yu fangzhi xuebao
This study focuses on the region along the Lanzhou-Chengdu-Chongqing (Lan-Cheng-Yu) refined oil pipeline, analyzing the development characteristics of geological hazards based on field-surveyed disaster points along the pipeline.
Weike ZHANG, Jian ZHOU, Yishun JIANG, Daojing GUO, Minggao TANG   +4 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Geological Hazard Susceptibility Assessment Based on the Combined Weighting Method: A Case Study of Xi’an City, China

Geosciences
Xi’an, China, has a complex geological environment, with geological hazards seriously hindering urban development and safety. This study analyzed the conditions leading to disaster formation and screened 12 evaluation factors (e.g., slope and slope ...
Peng Li, Wei Sun, Chang-Rao Li, Ning Nan, Sheng-Rui Su   +4 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Land Subsidence Monitoring and Susceptibility Assessment Integrating InSAR With OLS-MGWR-AHP: A Case Study Over Jiangdong New District, Haikou City

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Land subsidence is a geological hazard with complex spatiotemporal evolution. Accurate monitoring and scientific susceptibility assessment of land subsidence are of great importance for disaster prevention, mitigation, and urban planning.
Lianhuan Wei, Yaowu Feng, Yaxin Xu, Qiong Liu, Meng Ao, Jun Hu, Cristiano Tolomei, Christian Bignami   +7 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source