Results 171 to 180 of about 503,154 (248)

Association study of the KCNJ3 gene as a susceptibility candidate for schizophrenia in the Chinese population [PDF]

, 2011
Kazuo Yamada, Yoshimi Iwayama, Tomoko Toyota, Tetsuo Ohnishi, Hisako Ohba, Motoko Maekawa, Takeo Yoshikawa   +6 more
openalex   +1 more source

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

Advanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo, Nguyen Thi Nguyen, LiLi Guo, Ngoc Man Phan, Hyunsu Shin, Tae‐il. Kim, Yu Seok Youn, Jaeyun Kim   +7 more
wiley   +1 more source

Exploring Candidate Genes for Epilepsy by Computational Disease-Gene Identification Strategy

Balkan Journal of Medical Genetics, 2010
Sha Y, Liu Q, Wang Y, Dong C, Song L
doaj   +1 more source

Engineering tomato disease resistance by manipulating susceptibility genes. [PDF]

Front Genome Ed
Wang D, Mandal P, Rahman MS, Yang L.
europepmc   +1 more source

Feasibility of establishing deletion of the late cornified envelope genes LCE3B and LCE3C as a susceptibility factor for psoriasis

, 2016
Iffat Hassan, Safia Bashir, Sabhiya Majid, YasmeenJabeen Bhat, Rabia Farooq   +4 more
openalex   +1 more source

A Single‐Metal‐Doped Nanoplatform for Ferroptosis‐Driven cGAS‐STING Pathway Activation in Hepatocellular Carcinoma Immunotherapy

Advanced Functional Materials, EarlyView.
The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang, Shuang Feng, Jie Luo, Kaige Xu, Junfeng Guo, Xingyue Zhang, Mengxue Yuan, Qiang Luo, Yu Huang, Chaoqiang Fan, Kibret Mequanint, Donghui Zhu, Malcolm Xing, Shiming Yang   +13 more
wiley   +1 more source

Genetic insights into alcohol-associated liver disease: integrative transcriptome-wide analysis identifies novel susceptibility genes. [PDF]

Front Med (Lausanne)
Wang Q, Wang Z, Hu M, Liu F, Wang Z.
europepmc   +1 more source

Resequencing the susceptibility gene, ITGAM, identifies two functionally deleterious rare variants in systemic lupus erythematosus cases [PDF]

, 2014
Amy L. Roberts, Ellen Thomas, Shriram G. Bhosle, Laurence Gamé, O. A. Obraztsova, Timothy J. Aitman, Timothy J. Vyse, Benjamin Rhodes   +7 more
openalex   +1 more source

Electron–Matter Interactions During Electron Beam Nanopatterning

Advanced Functional Materials, EarlyView.
This article reviews the electron–matter interactions important to nanopatterning with electron beam lithography (EBL). Electron–matter interactions, including secondary electron generation routes, polymer radiolysis, and electron beam induced charging, are discussed.
Camila Faccini de Lima, Prathiba Thamizhavel, Taylor J. Woehl   +2 more
wiley   +1 more source

Data presented in the PhD thesis "Cucumber Mildew Resistance Identification of Cucumber Genes Involved in Susceptibility and Resistance to Powdery and Downy Mildew"

, 2019
Jeroen A. Berg
openalex   +1 more source