Identification of candidate susceptibility genes for cutaneous malignant melanoma through integrated multi-method analysis. [PDF]
Zhou P, Jiang X, Wang W, Wang D.
europepmc +1 more source
Implantable optoelectrical devices are an effective resource for the modulation and monitoring of neural activity with high spatiotemporal resolution. This review discusses current challenges faced by these devices and outlines future perspectives for the development of next‐generation neural interfaces targeting chronic, multisite, and multimodal ...
Stella Aslanoglou +4 more
wiley +1 more source
Identification of breast cancer susceptibility genes via trans-ethnic Mendelian randomization and colocalization analyses. [PDF]
Huang K, Huang H, Ma LL, Liu Y, Li Q.
europepmc +1 more source
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram +10 more
wiley +1 more source
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan +12 more
wiley +1 more source
Cross-tissue transcriptome-wide association studies identify genetic susceptibility genes for prostate cancer. [PDF]
Hua J +8 more
europepmc +1 more source
Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang +4 more
wiley +1 more source
Identification of a Sjogren\u27s syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons [PDF]
et al.,, Huang, Andrew J. W.
core +1 more source
A Cross-Tissue Transcriptome-Wide Association Study Identified Susceptibility Genes for Intervertebral Disc Degeneration. [PDF]
Zhang L, Zhao W, Yang H, Deng T, Li Y.
europepmc +1 more source

