Results 201 to 210 of about 583,132 (315)

Elucidating the susceptibility genes between insomnia and migraine by integrating genetic data and transcriptomes. [PDF]

J Headache Pain
Wang T, Li J, Yao Y, Wang H, Zheng X.
europepmc   +1 more source

Bioprinting High‐Cell‐Density Cardiac Tissue Constructs With Sustained Contractile Function

Advanced Healthcare Materials, EarlyView.
Contractile cardiomyocytes in 3D culture provide insights into the behavior of the heart. Combining a 3D bioprinting approach with a multi‐electrode array allows the development of the 3D culture to be monitored over time, and matured cultures allow the effect of drugs on cardiac function to be modelled, replicating effects seen in clinical application.
Priscila Melo, Wing Tai Tung, Harvey Lewis, Kavin Hettiarachchilage, Babis Tzivelekis, Rolando Berlinguer‐Palmini, Ana Marina Ferreira, Jason Gill, Kenneth Dalgarno   +8 more
wiley   +1 more source

Variant reclassification in cancer susceptibility genes and an updated variant spectrum of Turkish breast and colorectal cancer patients. [PDF]

Hum Genomics
Can ND, Akcay IM, Celik E, Ciftci C, Unal B, Agaoglu NB, Doganay HL, Dinler Doganay G.   +7 more
europepmc   +1 more source

Multifunctional Catechol‐Functionalized Cellulose Hydrogels for the Minimally Invasive Treatment of Acute Optic Nerve Injuries

Advanced Healthcare Materials, EarlyView.
Catechol‐functionalized cellulose hydrogels are developed as injectable, bioadhesive platforms for retinal neuroprotection. The hydrogels exhibit tunable rheological and mechanical properties, strong tissue adhesion, and sustained antioxidative activity.
Kai‐Hsiang Chang, Yi‐Ke Lin, Wei‐Li Chen, Ta‐Ching Chen, Jiashing Yu   +4 more
wiley   +1 more source

Risk Tier, Variant Certainty, and Real-World Care Patterns in Breast Cancer Patients with Germline Alterations in Breast Cancer Susceptibility Genes. [PDF]

Cancers (Basel)
Baydaş T, Ökten İN, Özen F, Emre S, Çil İ, Eser M, Gündoğdu A, Yılmaz OC, Gümüş M.   +8 more
europepmc   +1 more source

Encoded Cell‐Material Interactions to Reroute Cytokine Signaling for Regenerative Medicine

Advanced Healthcare Materials, EarlyView.
We present native MATRIX (Material Activated To Regulate Inducible gene eXpression), a co‐engineered material‐cell platform. Surfaces functionalized with antibodies for endogenous soluble ligands (e.g., IL‐1β or IL‐6) capture and immobilize ligands for presentation to a cognate, engineered synthetic Notch receptor, releasing a transcription factor (TF)
Zachary M. Eidman, Jhanvi Sharma, Joanne C. Lee, Nicholas F. Schulze, Hannah J. Brien, Kevin C. Corn, Marjan Rafat, Jonathan M. Brunger   +7 more
wiley   +1 more source

Exploring Candidate Genes for Epilepsy by Computational Disease-Gene Identification Strategy

Balkan Journal of Medical Genetics, 2010
Sha Y, Liu Q, Wang Y, Dong C, Song L
doaj   +1 more source

Identifying sepsis susceptibility genes in post-surgical patients using an artificial intelligence approach. [PDF]

Front Med (Lausanne)
Vaquerizo-Villar F, Hernandez-Beeftink T, Heredia-Rodríguez M, Gómez-Sánchez E, Lorenzo-López M, López-Herrero R, Bardaji-Carrillo M, Tamayo-Velasco Á, Martín-Fernández M, Sánchez-de-Prada L, Álvarez-Escudero J, Veiras S, Baluja A, Gonzalo-Benito H, Martínez-Paz P, García-Concejo A, Fernández-Rodríguez A, Jiménez-Sousa MA, Resino S, Martínez-Campelo L, Suárez-Pajés E, Quintela I, Cruz R, Carracedo Á, Villar J, Flores C, Hornero R, Tamayo E.   +27 more
europepmc   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Pathogenic Germline Variants in Cancer Susceptibility Genes.

JAMA
Idumah G, Newell D, Hadrys M, Ribaudo I, Ni Y, Arbesman J.   +5 more
europepmc   +1 more source