Results 131 to 140 of about 5,963,630 (346)

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Assessment of the Susceptibility of Urban Flooding Using GIS with an Analytical Hierarchy Process in Hanoi, Vietnam

open access: yesSustainability
The incidence of floods is rapidly increasing globally, causing significant property damage and human losses. Moreover, Vietnam ranks as one of the top five countries most severely affected by climate change, with 1/3 of residents facing flood risks ...
H. Nguyen, Hiroatsu Fukuda, M. Nguyen
semanticscholar   +1 more source

Moluccan Islands 1:125,000 [cartographic material] /

open access: yes, 1943
1st ed. - AMS 1. Relief shown by hachures, spot sheights, and contours.; "Work Projects Administration Project, O.P. 165-200-3"; Standard map series designation: [Series] A.M.S.
United States. Army Map Service. Indianapolis Unit.
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Landslide susceptibility assessment using different rainfall event-based landslide inventories: advantages and limitations

open access: yesNatural Hazards
The present work aims to evaluate potential sources of uncertainty associated with rainfall-triggered event-based landslide inventories within the framework of landslide susceptibility assessment. Therefore, this study addresses the following questions: (
S. Oliveira   +5 more
semanticscholar   +1 more source

Mapping Functional Susceptibilities in AML

open access: yesThe Hematologist, 2020
Lane, Steven, Henden, Andrea
openaire   +2 more sources

Clason's Guide to Texas: With Map of Auto Routes

open access: yes, 1917
Map of the state of Texas and surrounding areas. Individual counties are outlined in green and labeled with roads marked in red and railroads marked in black. Geographic features are marked with relief shown by hachures.
Clason Map Co.
core  

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Japan road map 1:1,000,000 [cartographic material]/

open access: yes, 1945
Various eds. Road map series of Japan and Korea showing transportation, water features and populated places. Relief shown by shading and spot heights.; Standard map series designation: [Series] A.M.S.
United States. Army Map Service.
core  

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

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