Results 111 to 120 of about 5,963,630 (346)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Natural hazards map of the Circum-Pacific Region [cartographic material] : Pacific Basin sheet /

open access: yes, 1992
Map modified 1992.; Depths shown by isolines.; "This map is a contribution to the International Decade for Natural Disaster Reduction (IDNDR)."; Accompanied by: Explanatory notes for the Natural hazards map of the Circum-Pacific region Pacific Basin ...
Circum-Pacific Map Project.
core  

Integrating Expert Knowledge with Statistical Analysis for Landslide Susceptibility Assessment at Regional Scale

open access: yesGeosciences, 2016
In this paper, an integration landslide susceptibility model by combining expert-based and bivariate statistical analysis (Landslide Susceptibility Index—LSI) approaches is presented.
Christos Chalkias   +3 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Flood Susceptibility Analysis with Integrated Geographic Information System and Analytical Hierarchy Process: A Multi-Criteria Framework for Risk Assessment and Mitigation

open access: yesWater
Flooding is among the most destructive natural disasters globally, and it inflicts severe damage on both natural environments and human-made structures.
Sujan Shrestha   +4 more
semanticscholar   +1 more source

Austin 1921 New Key Map

open access: yes, 1921
Sanborn map key for Austin in Travis County, Texas, showing the areas covered by numbered map sheets that contain more precise details related to risk assessment for fire ...
Sanborn Map Company
core  

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Asia transportation map 1:2 000 000 [cartographic material] : Burma /

open access: yes, 1945
Edition 2-AMS. Map of Burma showing international boundaries, transportation, water features and populated places.; Standard map series designation: Series 5201.; Also available online http://nla.gov.au/nla.map-vn676361.Series ...
United States. Army Map Service.
core  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Landslide Susceptibility Mapping in Darjeeling Himalayas, India

open access: yesAdvances in Civil Engineering, 2018
Landslide susceptibility map aids decision makers and planners for the prevention and mitigation of landslide hazard. This study presents a methodology for the generation of landslide susceptibility mapping using remote sensing data and Geographic ...
Amit Chawla   +5 more
doaj   +1 more source

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