Results 91 to 100 of about 302,377 (251)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Imaging of hip trauma - occult, suspect and concomitant fractures [PDF]

open access: yes, 2016
Background: Between one and nine percent of all hip fractures are occult or suspect and further examinations with computed tomography (CT) and/or magnetic resonance imaging (MRI) are vital for further handling.
Collin, David
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

[News Clip: Suspect arrested]

open access: yes, 1960
Video footage from the WBAP-TV television station in Fort Worth, Texas, to accompany a news story about a suspected burglar being arrested at his home in Fort ...
WBAP-TV (Television station : Fort Worth, Tex.)
core   +1 more source

PARTICIPNT TO THE CRIMINAL PROCEEDINGS ON THE SIDE OF DEFENCE IN THE CRIMINAL PROCEEDINGS OF THE RUSSIAN FEDERATION

open access: yesСрпска правна мисао
The main characteristics of the adversarial type of criminal proceedings in the Russian Federation are: a clear separation and demarcation of the parties in the criminal prosecution, defence and resolution of the criminal case and the procedural ...
Miodrag N. Simović
doaj  

PROBLEM OF DETERMINING ILLEGALITY OF DETENTION (ART. 301 § 2 OF THE CRIMINAL CODE OF THE RUSSIAN FEDERATION)

open access: yesВестник Кемеровского государственного университета, 2013
The paper is devoted to analysing and defining the criteria of illegality of detention that allow adjudicating the presence or absence of corpus delicti provided in Art. 301 §2 of the Criminal code of the Russian Federation.
I. A. Gaag
doaj  

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

PRE-COURT AGREEMENT ON COOPERATION AND PROSECUTOR'S ROLE IN ITS ACHIEVING AND FULFILLMENT

open access: yesRussian Journal of Economics and Law, 2010
In June 2009 a new institution is introduced into the Russian Criminal-Procedural Code, i.e. the pre-court agreement on cooperation. The article discusses the issue of the prosecutor's functions during its formation, as well as the issues of rights and ...
E. G. Shadrina
doaj  

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