Results 71 to 80 of about 302,377 (251)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
[News Clip: Suspect shoots self?]
, 1959 Video footage from the WBAP-TV station in Fort Worth, Texas to accompany a news story about a Dallas robbery suspect being found shot in the ...
WBAP-TV (Television station : Fort Worth, Tex.)
core
, 1958 Video footage from the WBAP-TV station in Fort Worth, Texas to accompany a news story about J. C.
WBAP-TV (Television station : Fort Worth, Tex.)
core +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
[News Clip: Robbery suspect Fort Worth]
, 1958 Video footage from the WBAP-TV station in Fort Worth, Texas to accompany a news story about Tarrant County authorities questioning a robbery ...
WBAP-TV (Television station : Fort Worth, Tex.)
core
Presence of a third party during procedural acts in preparatory proceedings involving a suspect
Ius NovumThe article analyses a new regulation in Polish criminal procedure. The Act of 14 April 2023, amending the Code of Criminal Procedure introduced a new right for the suspect, i.e. the possibility of the presence of a legal representative, actual guardian,
Radosław Koper
doaj +1 more source
Examining Violent Police-Citizen Encounters in South Africa: A Focus on Suspect and Police Behaviour [PDF]
E-Journal of Humanities, Arts and Social SciencesNumerous grievances have been lodged against police officers who abused their mandate to use force, which is a matter that has raised serious concern not only in policing circles but in the media as well.
Philisiwe Hadebe
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Bulletin of Kharkiv National University of Internal AffairsBased on the analysis of the criminal procedure legislation and generalisation of theoretical developments, the article identifies some peculiarities of legal regulation of the institute of special criminal proceedings (in absentia).
M. М. Kolomoitsev
doaj +1 more source