Results 111 to 120 of about 180,384 (297)

Descriptive Analysis of Sexual Assault Incidents Reported to Alaska State Troopers: 2003-2004 [PDF]

, 2007
This study examines the characteristics of sexual assault and sexual abuse of minor incidents reported to the Alaska State Troopers (AST), providing the first statewide overview of such cases.
Postle, Greg, Rosay, André B., TePas, Katherine, Wood, Darryl S.   +3 more
core  

Screening tuberculosis suspects: How many sputum specimens are adequate?

Annals of Tropical Medicine and Public Health, 2012
Background: The aim of the study was to assess whether the number of sputum samples for screening of tuberculosis suspects could be minimized. Materials and Methods: It was a hospital-based cross-sectional study conducted from December 2006 to May 2008.
SyedArshad Hussain, Ali Imtiyaz, Shamila Hamid   +2 more
openaire   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Serological Screening of Suspected COVID-19 Patients in Pakistan.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2021
To determine the antibody levels (IgM and IgG), using ELISA in suspected patients of COVID-19.Descriptive cross-sectional study. Place & Duration of Study: Real Time PCR Diagnostic and Research Laboratory, Peshawar, Khyber Pakhtunkhwa, Pakistan, from May to July 2020.A total of 94 blood specimens were collected from suspected COVID-19 patients.
Sajid, Ali, Anees, Muhammad, Tariq, Mehar, Najeeb Ur, Rehman, Nourin, Mehmood, Waseem, Iqbal   +5 more
openaire   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Identification of unknowns in real wastewater through the application of a LC-QTOF-MS based workflow [PDF]

, 2015
Wastewater contains a high number of organic micropollutants and transformation products of environmental concern. Recent approaches, combining methodologies based on target and suspect screening (for suspected substances based on prior information but ...
Aalizadeh, Reza, Bletsou, Anna A., Gago-Ferrero, Pablo, Thomaidis, Nikolaos S.   +3 more
core  

A Droplet State in an Interacting Two-Dimensional Electron System

, 1999
It is well known that the dielectric constant of two-dimensional (2D) electron system goes negative at low electron densities. A consequence of the negative dielectric constant could be the formation of the droplet state. The droplet state is a two-phase
A. Isihara, B. Tanatar, E. Abrahams, G. Meissner, Hock-Kee Sim, Junren Shi, P. A. Lee, S. He, S. T. Chui, S. V. Kravchenko, S. V. Kravchenko, Song He, X. C. Xie   +12 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

A Novel Liquid Chromatographic Time-of-Flight Tandem Mass Spectrometric Method for the Determination of Secondary Metabolites in Functional Flours Produced from Grape Seed and Olive Stone Waste

Molecules
Agricultural by-products like grape pomace and olive stones are rich in bioactive compounds and can be processed into grape seed and olive stone flours.The phenolic composition of such flours still remains underexplored.
Achilleas Panagiotis Zalidis, Natasa P. Kalogiouri, Ioannis Mourtzinos, Dimitris Sarris, Konstantinos Gkatzionis   +4 more
doaj   +1 more source