Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Procedimiento de preparación, conservación, y uso en peces, del probiótico SHEWANELLA PUTREFACIENS PDP 11 para el control de enfermedades y la mejora en el crecimiento [PDF]
, 2012 Número de solicitud 201100385Procedimiento de preparación, conservación, y uso en peces, del probiótico Shewanella putresfaciens Pdp11 para el control de enfermedades y la mejora en el crecimiento.
Alarcón López, Francisco Javier +6 more
core
Sensitization profiles to purified plant food allergens among pediatric patients with allergy to banana. [PDF]
, 2011 Banana fruit allergy is well known, but neither immunoglobulin E recognition patterns to purified plant food allergens nor true prevalences of putative banana allergens have been established. This study aimed to characterize β-1,3-glucanase and thaumatin-
Bobolea, Irina +7 more
core +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Algunas precisiones sobre la suspensión del concurso de acreedores en el Derecho uruguayo
Revista de la Facultad de Derecho, 2014 El propósito del presente artículo es realizar una crítica constructiva del actual régimen de suspensión del concurso de acreedores regulado en la Ley Nº 18.387 de Declaración Judicial del Concurso y Reorganización Empresarial (LCU).
Diego Mongrell González
doaj +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Divided we stand: Parallel distributed stack memory management [PDF]
, 1994 We present an overview of the stack-based memory management techniques that we used in our non-deterministic and-parallel Prolog systems: &-Prolog and DASWAM.
Hermenegildo, Manuel V., Kish, Shen
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
El desarrollo del sistema de educación superior analizado desde las figuras jurídicas de suspensión y extinción de universidades y escuelas politécnicas [PDF]
, 2016 El presente trabajo es un análisis constitucional, legal y doctrinal del principio de calidad dela educación superior, de las figuras de suspensión y extinción, así como de sus implicaciones, ya que son parte del conjunto de medidas y políticas que ...
Torres Gómez, Hernán Patricio
core