Results 31 to 40 of about 359,477 (267)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Fluids, 2020 The rheology of macroscopic particle suspensions is relevant in many industrial applications, such as cement-based suspensions, synthetic and natural drilling fluids.
Regina Miriam Parlato +5 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Effect of cooling rate on the microstructure and porosity of alumina produced by freeze casting [PDF]
Journal of the Serbian Chemical Society, 2012 Freeze casting is a well-known shaping technique to produce materials with directional porosity. One of the major problems is the difficulty to control the cooling rate thus leading to gradients in pore size and homogeneity.
Nieto Isabel María +2 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Release of selected amino acids from zinc carriers
Acta Pharmaceutica, 2016 The paper deals with the results of an investigation of the release of selected amino acids (histidine, tryptophan, tyrosine) from model suspensions prepared by co-precipitation with zinc chloride.
Dyja Renata +2 more
doaj +1 more source
Engineering Structures and Technologies, 2014 In this paper, the stability of aqueous suspensions of multiwalled carbon nanotubes (MWCNTs) has been studied with physical and chemical methods. The optimum dispersion time of MWCNT suspension in a rotary homogenizer has been found.
Alena Politaeva +2 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
An optimal self-excited heating method for biogas production under cold climate
The Journal of Engineering, 2019 Biogas, as the product of anaerobic fermentation, is one of the main routes to utilize bioenergy. The biogas production rate is determined by lots of factors, of which temperature determines most. However, when operating in the cold climate or cold areas,
Hanyu Yang +6 more
doaj +1 more source