Results 61 to 70 of about 712,286 (285)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Drying of complex suspensions

open access: yes, 2010
We investigate the 3D structure and drying dynamics of complex mixtures of emulsion droplets and colloidal particles, using confocal microscopy. Air invades and rapidly collapses large emulsion droplets, forcing their contents into the surrounding porous
Alexis Bergès   +9 more
core   +1 more source

Optical Limiting in Single-walled Carbon Nanotube Suspensions [PDF]

open access: yes, 2000
Optical limiting behaviour of suspensions of single-walled carbon nanotubes in water, ethanol and ethylene glycol is reported. Experiments with 532 nm, 15 nsec duration laser pulses show that optical limiting occurs mainly due to nonlinear scattering ...
A. Govindaraj   +19 more
core   +3 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

African American Male Achievement Initiative: A Closer Look At Suspensions Of African American Males In OUSD [PDF]

open access: yes, 2012
This report examines the data, literature, and policy around suspensions of African American male students to uncover and better understand the disparities between this group and all other ethnic and gender groups.
Alison Feldman   +6 more
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Reología de suspensiones de esmaltes cerámicos para monococción: estudio de la influencia de los aditivos utilizados

open access: yesBoletín de la Sociedad Española de Cerámica y Vidrio, 1999
In this paper are presented the results obtained by the characterisation and the study of the rheological behavior of concentrated frits suspensions used in the preparation of ceramic glazes for single firing porous tiles.
Andreola, F., Pozzi, P., Romagnoli, M.
doaj  

The suspensions scandal

open access: yesJournal of Obstetrics and Gynaecology, 2003
The process by which senior hospital doctors are disciplined within the National Health Service is analysed. The mechanisms used are discussed and a number of faults are identified. Many of these faults give an unfair advantage to management and are contrary to the rules of 'Natural Justice'.
openaire   +2 more sources

Particle-scale statistical theory for hydrodynamically induced polar ordering in microswimmer suspensions

open access: yes, 2018
Previous particle-based computer simulations have revealed a significantly more pronounced tendency of spontaneous global polar ordering in puller (contractile) microswimmer suspensions than in pusher (extensile) suspensions.
Hoell, Christian   +2 more
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

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