Results 91 to 100 of about 1,657,321 (297)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Trans-disciplinary Research: An Academic-Practitioner Partnership Effort on Investigating the Relationship between the Cooperative Model and Sustainability

RIMCIS, 2015
This article details novel research methodology developed through a researcher-practitioner partnership and employed in a three-phase research effort that explored relationships between the co-operative model and sustainable development.
Robert Newell, Ann Dale, Yuill Herbert, Fiona Duguid, Rebecca Foon, Peter Hough   +5 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Summary Report - Think Tank 3: Sport & Sustainability — Universities as Agents for Change

, 2013
Kinesiology, School ofEducation, Faculty ...
Centre for Sport and Sustainability
core   +1 more source

Crossing thresholds: conceptual transformation in ecological economics education

Sustainability: Science, Practice, & Policy
This Brief Report examines changes in students’ understanding of economics and “the economy” through the lens of “threshold concepts,” which serve as gateways to new ways of thinking.
Richard Bärnthaler, Felix Barbour, Marie Berthet, Milena Büchs, Alice Damiano, Richard Itaman, Diana Ivanova, Aidan Knox, Gina Moran, Jouni Paavola, Thomas Webb   +10 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Economic Performance and Sustainability Challenges of Broiler Production in Egypt: A Case Study in Qalyub Governorate [PDF]

This study investigates the economic performance and sustainability challenges of broiler production in Egypt, focusing on Qalyubia Governorate. It addresses the persistent national white meat deficit, suboptimal self-sufficiency, and significant market ...
Elshahat, Elzaabalawy Mohamed, Aram, Samir Attia, Shoaib, Nashwa Samir, Alhfny, Ibrahim Mohammad Abd Elaziz   +3 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Sustainability Reporting. The Romanian Sustainability Code

CECCAR Business Review
With this article we want to highlight the way of reporting on sustainability. We need to be aware of why these reports are necessary and also to know the benefits of the Romanian Sustainability Code (CRS), how we use the CRS platform, what are the CRS ...
Elena STĂNCIULESCU
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source