Results 71 to 80 of about 2,733,914 (301)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Linking concepts of change and ecosystem services research: A systematic review

open access: yesChange and Adaptation in Socio-Ecological Systems, 2018
Transformation, transition and regime shift are increasingly applied concepts in the academic literature to describe changes in society and the environment.
Rau Anna-Lena   +14 more
doaj   +1 more source

WGV: An Australian Urban Precinct Case Study to Demonstrate the 1.5 °C Agenda Including Multiple SDGs

open access: yesUrban Planning, 2018
The WGV project is an infill residential development in a middle suburb of Perth, Western Australia. Its urban planning innovation is in its attempt to demonstrate net zero carbon as well as other sustainability goals set by urban planning processes such
Jason Wiktorowicz   +5 more
doaj   +1 more source

Sustainability- considering the pillars of sustainability as a theoretical paradigm [PDF]

open access: yes, 2008
The need for a common theoretical framework and underpinning with regards to the use of the term ‘sustainability’ in connection with food is important.
Caraher, M.
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Trans-disciplinary Research: An Academic-Practitioner Partnership Effort on Investigating the Relationship between the Cooperative Model and Sustainability

open access: yesRIMCIS, 2015
This article details novel research methodology developed through a researcher-practitioner partnership and employed in a three-phase research effort that explored relationships between the co-operative model and sustainable development.
Robert Newell   +5 more
doaj   +1 more source

Sustainability charter and sustainable mobility

open access: yes, 2022
In order to make our cities more sustainable, the paper describes a research aimed at defining a new urban tool in the context of Agenda 2030. It is the 'Sustainability Charter', a tool that already exists at the international level, but here is analyses at the local level as a result of decision-making process which refers to a set of interactions ...
Spadaro I., Pirlone F., Candia S.
openaire   +2 more sources

Sustainability assessment and complementarity [PDF]

open access: yes, 2016
Sustainability assessments bring together different perspectives that pertain to sustainability in order to produce overall assessments and a wealth of approaches and tools have been developed in the past decades. But two major problematics remain.
Alrøe, Hugo F., Noe, Egon
core   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Sustainable Tourism, Towards Sustainable Development [PDF]

open access: yes, 2018
Following the previous two chapters on sectorial applications of sustainable project management, the tourism sector has been identified as one of the most influential contributors to the economic growth of many developing countries. The growing influence of the tourism sector as an economic powerhouse and its potential as a tool for development are ...
Ljubomir Janjusevic, Mohamed Salama
openaire   +1 more source

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