Results 71 to 80 of about 3,545,676 (334)
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
RIMCIS, 2015 This article details novel research methodology developed through a researcher-practitioner partnership and employed in a three-phase research effort that explored relationships between the co-operative model and sustainable development.
Robert Newell +5 more
doaj +1 more source
Governance for sustainability: learning from VSM practice [PDF]
, 2015 Purpose – While there is some agreement on the usefulness of systems and complexity approaches to tackle the sustainability challenges facing the organisations and governments in the twenty-first century, less is clear regarding the way such approaches ...
Espinosa, Angela
core +2 more sources
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Sustainability charter and sustainable mobility
, 2022 In order to make our cities more sustainable, the paper describes a research aimed at defining a new urban tool in the context of Agenda 2030. It is the 'Sustainability Charter', a tool that already exists at the international level, but here is analyses at the local level as a result of decision-making process which refers to a set of interactions ...
Spadaro I., Pirlone F., Candia S.
openaire +2 more sources
SiD - Table of Contents / Sumário
Sustentabilidade em Debate, 2023 SiD - Sustainability in Debate
doaj +6 more sources
Understanding (and tackling) need satisfier escalation
Sustainability: Science, Practice, & Policy, 2020 Contemporary consumption patterns, embedded in profit-maximizing economic systems, are driving a worsening socio-ecological crisis, in particular through the escalating production and consumption of goods with high material and/or energy intensity ...
Lina I. Brand-Correa +3 more
doaj +1 more source
Transforming innovation for sustainability [PDF]
, 2012 The urgency of charting pathways to sustainability that keep human societies within a "safe operating space" has now been clarified. Crises in climate, food, biodiversity, and energy are already playing out across local and global scales and are set to ...
Arond, Elisa +11 more
core +2 more sources