Results 71 to 80 of about 2,796,465 (333)
Understanding (and tackling) need satisfier escalation
Sustainability: Science, Practice, & Policy, 2020 Contemporary consumption patterns, embedded in profit-maximizing economic systems, are driving a worsening socio-ecological crisis, in particular through the escalating production and consumption of goods with high material and/or energy intensity ...
Lina I. Brand-Correa +3 more
doaj +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source
Scientific ReportsDairy farmers are grappling with serious business challenges, including rising operational costs, labour shortages, unstable milk prices, changing consumer preferences, long hours with minimal downtime and unstable weather patterns due to climate change ...
Esra Celik +3 more
doaj +1 more source
SUSTAINED HYPERTENSION FOLLOWING THE ADMINISTRATION OF DESOXYCORTICOSTERONE ACETATE [PDF]
, 1951 Sydney M. Friedman +2 more
openalex +1 more source
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Molecular Oncology, EarlyView.Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren +4 more
wiley +1 more source
Phaeochromocytoma with Sustained Hypertension [PDF]
, 1956 K.N.V. Palmer, G. A. McDonald
openalex +1 more source
Robots and Social Sustainability [PDF]
arXivSustainability is no longer a matter of choice but is invariably linked to the survival of the entire ecosystem of our planet Earth. As robotics technology is growing at an exponential rate, it is crucial to examine its implications for sustainability. Our focus is on social sustainability, specifically analyzing the role of robotics technology in this
arxiv
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
Revisiting CDKN2A dysregulation in Ewing sarcoma
Molecular Oncology, EarlyView.We revisit CDKN2A to investigate its role as a potential prognostic biomarker in Ewing sarcoma using data from pre‐clinical models as well as clinical samples. Ewing sarcoma (EwS) is a rare and aggressive malignancy, which frequently affects children.
Anjali Paragji +8 more
wiley +1 more source