Results 131 to 140 of about 15,140,369 (361)

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

The role of sustainability assessment in sustainability management for urban redevelopment [PDF]

open access: yes, 2015
Sustainability assessment has the potential to influence decision making and hence to improve the management of sustainability. This paper presents the development and reporting of benchmark sustainability indicators and discusses the challenges of ...
Blackwood, David   +4 more
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Why Pakistani Small and Medium Enterprises are Not Reporting on Sustainability Practices? [PDF]

open access: yesPakistan Journal of Commerce and Social Sciences, 2017
This paper seeks to understand why Pakistani SMEs are not reporting on sustainability practices. Also, this paper aims to understand the sustainability reporting patterns of SMEs worldwide.
Zeeshan Mahmood
doaj  

Mapping sustainability reporting research with the UN's sustainable development goal. [PDF]

open access: yesHeliyon, 2023
Raman R   +6 more
europepmc   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

PENGARUH SUSTAINABILITY REPORTING BERDASARKAN GLOBAL REPORTING INITIATIVE TERHADAP KINERJA KEUANGAN PERUSAHAAN SYARIAH DI INDONESIA [PDF]

open access: yes, 2017
Research trends regarding sustainability reporting begin to increase gradually in Indonesia, as well as the increasing of companies that publish sustainability reporting. However, many of these studies still show inconsistent results.
SITI FACKRUNISAH
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

PENGARUH KARAKTERISTIK DEWAN KOMISARIS TERHADAP PENGUNGKAPAN SUSTAINABILITY REPORTING DENGAN UKURAN PERUSAHAAN SEBAGAI VARIABEL MODERASI (Studi Empiris pada Perusahaan Manufaktur yang terdaftar di BEI Tahun 2014- 2015) [PDF]

open access: yes, 2017
This research aims to analyze :(1) the influence of board commissioners characteristics on sustainability reporting (2) the influence of firm size as the moderating variable in relations between board commissioners characteristics and sustainability ...
AISYAH, Wulandari Siti, FUAD, Fuad
core  

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