Results 101 to 110 of about 1,366,775 (299)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
What is sustainability economics? [PDF]
While economists have been contributing to the discussion of various aspects of sustainability for decades, it is just recently that the term “sustainability economics” was used explicitly in the ecological, environmental, and resource economics ...
Martin F. Quaas, Stefan Baumgärtner
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The Discipline in Interdisciplinarity: Flagging a Blind-Spot in Sustainability Science [PDF]
Journal of Interdisciplinary Sciences, 2019 In the last few decades, sustainability science has developed into a formidable field of interdisciplinary scholarship aimed broadly at contributing to the global sustainability agenda. As a problem-driven science, sustainability science is necessarily
Chad S. Boda, Turaj Faran
doaj
Ecology and Society, 2010 Community-based conservation institutions can be conceptualized as complex adaptive systems that pass through a cycle of growth, maturation, collapse, and reorganization.
Nabin Baral +2 more
doaj +1 more source
Islands of Sustainability in Time and Space [PDF]
We review the economics perspective on sustainable resource use and sustainable development. Under standard conditions, dynamic efficiency leads to sustainability of renewable resources but not the other way around.
Christopher Wada +4 more
core
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Toward a Science of Sustainability [PDF]
, 2012 This report presents an overview of research horizons in sustainability science. Its motivation is to help harness science and technology to foster a transition toward sustainability – toward patterns of development that promote human well-being while ...
Clark, William C., Levin, Simon A.
core
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Improving Traffic Safety Through Video Analysis in Jakarta, Indonesia
, 2018 This project presents the results of a partnership between the Data Science for Social Good fellowship, Jakarta Smart City and Pulse Lab Jakarta to create a video analysis pipeline for the purpose of improving traffic safety in Jakarta.
Caldeira, João +10 more
core +1 more source