Results 141 to 150 of about 292,782 (296)
Synthesizing evidence in sustainability science through harmonized experiments: Community monitoring in common pool resources. [PDF]
Proc Natl Acad Sci U S A, 2021 Ferraro PJ, Agrawal A.
europepmc +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Sociology, Science and Sustainability: Developing Relationships in Scotland [PDF]
This paper considers the application of the sociological imagination during the analysis of data collected during an ethnographic study of an environmental regulator, the Scottish Environment Protection Agency (SEPA). SEPA is tasked with implementing the
Elizabeth A. Kirk +2 more
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Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Scientific literacy for sustainability
, 2006 We only need to consider public media reports to appreciate that there is growing concern amongst citizens for sustainability. This concern arises from increasing appreciation that the current direction and rate of exploitation of resources is not ...
Murcia, Karen
core
Ökologisches Wirtschaften - Fachzeitschrift, 1998 Der Weg zu einer nachhaltigen Entwicklung stellt insbesondere die Wissenschaft vor große Herausforderungen. Dabei ist ihr Beitrag ambivalent. Einerseits ermöglicht der wissenschaftliche Fortschritt Problemlösungen, andererseits werden durch die tiefen Eingriffe in komplexe natürliche Prozesse selbst wieder neue Probleme erzeugt.
openaire +2 more sources
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Urban sustainability science: prospects for innovations through a system's perspective, relational and transformations' approaches : This article belongs to Ambio's 50th Anniversary Collection. Theme: Urbanization. [PDF]
Ambio, 2021 Frantzeskaki N, McPhearson T, Kabisch N.
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