Results 31 to 40 of about 217,063 (254)
Unique Opportunities of Island States to Transition to a Low-Carbon Mobility System [PDF]
, 2020 Small islands developing states (SIDS) contribute minuscule proportions to global greenhouse gas (GHG) emissions and energy consumption, but are highly exposed to climate change impacts, in particular to extreme weather events and sea-level rise. However,
Blechinger, Philipp +2 more
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Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Economic Resilience of German Lignite Regions in Transition [PDF]
, 2019 This paper recalls the development of the German lignite regions Rhineland and Lusatia since 1945 to allow for a better understanding of their situation in 2019. We analyze their economic resilience, defined as adaptive capacity, using Holling’s adaptive
Oei, Pao-Yu +3 more
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The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
“Just” ecopreneurs: re-conceptualising green transitions and entrepreneurship [PDF]
, 2016 © 2016 Informa UK Limited, trading as Taylor & Francis Group. Economic, environmental, and social limits of the current capitalist mode of production have led to a rethinking and reconceptualisation of economic processes and models including the role ...
Affolderbach, Julia, Krueger, Rob
core +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
The politics of sustainability transitions [PDF]
Journal of Environmental Policy & Planning, 2016 Sustainability transitions are processes of fundamental social change in response to societal challenges (Grin, Rotmans, & Schot, 2010; Markard, Raven, & Truffer, 2012).
Avelino, F. +3 more
openaire +3 more sources
Ships passing in the night?: re-thinking the relationship between entrepreneurial agency and purposive transitions [PDF]
, 2009 In this paper, we examine the ways in which the phenomenon of entrepreneurial agency has been represented in the transitions literature with particular reference to purposive sustainability transitions.
Blundel, Richard, Monaghan, Adrian
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