Results 51 to 60 of about 24,963 (264)
Energy poverty is a multifaceted and urgent issue in the Global South, especially in South Africa, where, despite an electrification rate exceeding 90%, a substantial 40% of the population still experiences energy poverty.
Thandeka Tshabalala +2 more
doaj +1 more source
The water–energy–food (WEF) nexus is recognised globally as a framework for sustainable resource management and a potential tool for building resilient social-ecological systems (SES).
Lourens Swart +2 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The year 2024 marked nine of the 15-year timeline towards attaining the Sustainable Development Goals (SDGs). Consequently, questions arise regarding the progress made.
Godwell Nhamo +2 more
doaj +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
COVID-19 impacts on school operations: a pushback on the attainment of SDG 4 in South Africa
In May 2023, the World Health Organization declared that COVID-19 was no longer a public health emergency of international concern. However, this declaration does not remove severe negative impacts COVID-19 had on the education sector. This paper sets an
Godwell Nhamo +2 more
doaj +1 more source
Power in sustainability transitions
This chapter delves into the role of power in sustainability transitions, addressing the limited attention power dynamics have received in the field despite their centrality to lasting societal change. Drawing on theories of power from various disciplines, this chapter introduces two conceptual frameworks to analyse power: (1) “power to, over, and with”
Guilherme Raj +2 more
openaire +2 more sources
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
This study examines the perceptions of students about SDG localization in Zimbabwean universities. The study uses a mixed methods research design. The results reveal that students perceive the SDGs as significant in university curricula.
Lazarus Chapungu, Godwell Nhamo
doaj +1 more source

