Results 51 to 60 of about 24,963 (264)

Contextualising a multi-dimensional perspective on energy poverty for South Africa’s just energy transition: a systematic literature review

open access: yesEnvironmental Research: Energy
Energy poverty is a multifaceted and urgent issue in the Global South, especially in South Africa, where, despite an electrification rate exceeding 90%, a substantial 40% of the population still experiences energy poverty.
Thandeka Tshabalala   +2 more
doaj   +1 more source

Exploring a Water–Energy–Food (WEF) Nexus Approach to Governance: A Case Study of the V&A Waterfront in Cape Town, South Africa

open access: yesEnergies
The water–energy–food (WEF) nexus is recognised globally as a framework for sustainable resource management and a potential tool for building resilient social-ecological systems (SES).
Lourens Swart   +2 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Universities and Sustainable Development Goals localisation: insights from academic staff in Zimbabwe

open access: yesCogent Education
The year 2024 marked nine of the 15-year timeline towards attaining the Sustainable Development Goals (SDGs). Consequently, questions arise regarding the progress made.
Godwell Nhamo   +2 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

COVID-19 impacts on school operations: a pushback on the attainment of SDG 4 in South Africa

open access: yesCogent Education
In May 2023, the World Health Organization declared that COVID-19 was no longer a public health emergency of international concern. However, this declaration does not remove severe negative impacts COVID-19 had on the education sector. This paper sets an
Godwell Nhamo   +2 more
doaj   +1 more source

Power in sustainability transitions

open access: yes
This chapter delves into the role of power in sustainability transitions, addressing the limited attention power dynamics have received in the field despite their centrality to lasting societal change. Drawing on theories of power from various disciplines, this chapter introduces two conceptual frameworks to analyse power: (1) “power to, over, and with”
Guilherme Raj   +2 more
openaire   +2 more sources

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Status quo of sustainable development goals localisation in Zimbabwean universities: Students perspectives and reflections

open access: yesSustainable Futures
This study examines the perceptions of students about SDG localization in Zimbabwean universities. The study uses a mixed methods research design. The results reveal that students perceive the SDGs as significant in university curricula.
Lazarus Chapungu, Godwell Nhamo
doaj   +1 more source

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