Results 61 to 70 of about 213,310 (312)

Scaling the impact of sustainability initiatives: a typology of amplification processes

open access: yesUrban Transformations, 2020
Amplifying the impact of sustainability initiatives to foster transformations in urban and rural contexts, has received increasing attention in resilience, social innovation, and sustainability transitions research.
David P. M. Lam   +6 more
doaj   +1 more source

Ships passing in the night?: re-thinking the relationship between entrepreneurial agency and purposive transitions [PDF]

open access: yes, 2009
In this paper, we examine the ways in which the phenomenon of entrepreneurial agency has been represented in the transitions literature with particular reference to purposive sustainability transitions.
Blundel, Richard, Monaghan, Adrian
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Socio-technical transitions towards environmental sustainability through green ICT [PDF]

open access: yes, 2015
We adopt the broad conceptualisation of Green Information Communication Technology (ICT) used by the Organisation for Economic Cooperation and Development (OECD), incorporating perspectives on Information Technology (IT) and Information Systems (IS ...
Butler, T, Daly, M, Hackney, RA
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

How can we drive sustainability transitions?

open access: yesPolicy Design and Practice, 2022
Sustainability transitions are required to address challenges of climate change, economic development, ecological integrity, and social justice. Driving sustainability transitions is difficult but necessary work.
Michael Mintrom, Briony C. Rogers
doaj   +1 more source

The value of theoretical multiplicity for steering transitions towards sustainability [PDF]

open access: yes, 2009
Transition management, as a theory of directing structural societal changes towards sustainable system innovations, has become a major topic in scientific research over the last years.
Breeman, G.E.   +4 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Localization of sustainable development goals among non-teaching staff in higher education: the status quo dynamics at great Zimbabwe university

open access: yesFrontiers in Education
IntroductionThe influence of non-teaching staff on localizing Sustainable Development Goals (SDGs) within universities is underexplored despite its potential significance.
Isaac Nyambiya   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy