Results 51 to 60 of about 220,364 (303)

How can we drive sustainability transitions?

Policy Design and Practice, 2022
Sustainability transitions are required to address challenges of climate change, economic development, ecological integrity, and social justice. Driving sustainability transitions is difficult but necessary work.
Michael Mintrom, Briony C. Rogers
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Transdisciplinary curriculum design for sustainability transitions: A reflective dialogue

South African Journal of Science
Inter- and transdisciplinary curricula can potentially develop an integrated understanding of an increasingly interconnected, complex world and develop students’ agency, empathy, creativity and critical thinking skills.
Lausanne Olvitt, Megan Davies, A'ishah Ebrahim, Jessica Cockburn   +3 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Contextualising a multi-dimensional perspective on energy poverty for South Africa’s just energy transition: a systematic literature review

Environmental Research: Energy
Energy poverty is a multifaceted and urgent issue in the Global South, especially in South Africa, where, despite an electrification rate exceeding 90%, a substantial 40% of the population still experiences energy poverty.
Thandeka Tshabalala, Megan Davies, Nthabiseng Mohlakoana   +2 more
doaj   +1 more source

Exploring a Water–Energy–Food (WEF) Nexus Approach to Governance: A Case Study of the V&A Waterfront in Cape Town, South Africa

Energies
The water–energy–food (WEF) nexus is recognised globally as a framework for sustainable resource management and a potential tool for building resilient social-ecological systems (SES).
Lourens Swart, Mark Swilling, Amanda Gcanga   +2 more
doaj   +1 more source

Economic Resilience of German Lignite Regions in Transition [PDF]

, 2019
This paper recalls the development of the German lignite regions Rhineland and Lusatia since 1945 to allow for a better understanding of their situation in 2019. We analyze their economic resilience, defined as adaptive capacity, using Holling’s adaptive
Oei, Pao-Yu, Schöttker, Oliver, Stognief, Nora, Walk, Paula   +3 more
core   +1 more source

Transition to Sustainability

, 2023
AbstractCompanies are increasingly faced with the challenge of how to implement sustainability strategies in their business performances. This chapter discusses transition processes, presents mechanisms, and clarifies how tools and methodologies from Part II of this book can help companies in the transition process towards more sustainable practices ...
Fet, Annik Magerholm, Keitsch, Martina Maria   +1 more
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Universities and Sustainable Development Goals localisation: insights from academic staff in Zimbabwe

Cogent Education
The year 2024 marked nine of the 15-year timeline towards attaining the Sustainable Development Goals (SDGs). Consequently, questions arise regarding the progress made.
Godwell Nhamo, Lazarus Chapungu, Kaitano Dube   +2 more
doaj   +1 more source