Results 111 to 120 of about 2,302,279 (319)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Planning for a sustainable future : SDC consultation response
, 2012 This document is the Sustainable Development Commission's response to the consulation on 'Planning for a sustainable future : white paper'.Publisher ...
Sustainable Development Commission
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Applied SciencesSustainable shell structures are thin, curved systems such as domes, vaults, and cylindrical shells that achieve strength and stability primarily through membrane action, allowing significant material savings.
Cristina Veres, Maria Tănase
doaj +1 more source
SUSTAINABLE MARKETING FOR SUSTAINABLE DEVELOPMENT
, 2014 This paper aims to highlight the mutual interrelation between sustainable marketing and sustainable development. Sustainable development is viewed as an established three-dimensional concept comprising economic sustainability and prosperity, social equity and environmental quality.
Magaš, Dragan, Meler, Marcel
openaire +2 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
, 2012 This report is the Sustainable Development Commission's summary of 250 commitments contained within 'The UK Government sustainable development strategy'.
Sustainable Development Commission
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Digitalization in urban planning: new digital technologies for sustainable cities
TeMA: Journal of Land Use, Mobility and EnvironmentStarting from the relationship between urban planning and mobility management, TeMA has gradually expanded the view of the covered topics, always remaining in the groove of rigorous scientific in-depth analysis. This section of the Journal, Review Notes,
Annunziata D'Amico
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
I will if you will : towards sustainable consumption : a summary
, 2012 Report is summary of 'I will if you will : towards sustainable consumption : a summary'.Summary of the final report of the Sustainable Consumption Roundtable (Great Britain) sets out how a significant shift towards more sustainable lifestyles is possible
Sustainable Consumption Roundtable (Great Britain)
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Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source