Results 111 to 120 of about 4,669,831 (317)

Smart, Sustainable, Resilient, and Inclusive Cities: Integrating Performance Assessment Indicators into an Ontology-Oriented Scheme in Support of the Urban Planning Practice

Urban Science
The unprecedented pace of urbanization has been exerting significant strain on cities, raising critical concerns across environmental, economic, social, and technological aspects.
Maria Panagiotopoulou, Anastasia Stratigea, Margarita Kokla   +2 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

The Role of Landscape Architecture in Sustainable Urban Development: Implementation of Universal Design

RUAS
Landscape architecture significantly contributes to sustainable development by incorporating universal design principles in the design of public open spaces.
Nahdatunnisa, Fajar, M. Arzal Tahir, Ahsan Hidayat Setiadi   +3 more
doaj   +1 more source

Sustainable Jobs in Sustainable Energy : closing the gap [PDF]

, 2004
The surge in demand for renewable energy has seen the sector expand in recent years. Evidence of this in the North East is the recent establishment of an R&D centre (New and Renewable Energy Centre NaREC).
Alwan, Zaid, Fitzgerald, Ian
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Understanding influences on farmers' practices [PDF]

, 2013
Farming is a complex human activity system with many actors and many components. Farming is also an activity that has, in recent decades, been ascribed two major, but potentially conflicting, objectives: the short to medium term production of sufficient ...
Lane, Andrew, Oreszczyn, Sue
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Sustainable Waste Sorter [PDF]

, 2019
Indiana University Purdue University IndianapolisThe purpose of this project is to help people eliminate the confusion on whether they should throw their trash away or dispose of it in a recycling bin.
Garza, Elisabeth, Smerdel, Aaron, Staton, Jordan   +2 more
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Sustainable consumption futures: according to whom?

Sustainability: Science, Practice, & Policy
This article aims to uncover diverse perspectives regarding what sustainable consumption is and should be in the future. We draw upon and combine critical futures studies with recognitional justice.
Åsa Svenfelt, Noha Baraka Wadha, Vishal Parekh   +2 more
doaj   +1 more source