Results 141 to 150 of about 2,302,279 (319)
National infrastructure : embedding sustainable development in decision making
, 2012 By taking a sustainable development approach, local authorities and their partners can play a leading role in delivering integrated environmental, social and economic improvements at the local level.Publisher ...
Sustainable Development Commission
core
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
Sustainable development : third annual assessment of progress by the Scottish Government
, 2012 Contents: Sustainable development : third annual assessment of progress by the Scottish Government -- Annexe 1: Scottish Government indicator and target data -- Annexe 2: Scottish Government indicator and target analysis -- Annexe 3: Delivery on ...
Sustainable Development Commission Scotland
core
Sustainable or not sustainable?
Environmental degradation, scarcity of resources, and societal issues have been reshaping the strategic agendas and governance mechanisms of many organizations. From a traditional perspective, the duty of the board of directors (BOD) has always been to the owners and investors of the firm.
Chams, Nour||, García-Blandón, Josep
openaire +1 more source
Sustainability Science for Strong Sustainability
, 2014 The dynamism of science has been catalytic for human prosperity in recent history. Conventional perspectives of the ivory tower model of modern science are, however, rivalled by the failure of humanity to tackle global crises of an economic, environmental and social nature.
openaire +2 more sources
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
SDC challenge paper : measuring what matters in light of the Stiglitz Report
, 2012 This report is based on the 'Report by the Commission on the Measurement of Economic Performance and Social Progress' (Stiglitz Report, 2009).This paper was an input to Sustainable Development Commission Scotland’s work for the Carnegie United Kingdom ...
Sustainable Development Commission Scotland
core
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
, 2012 A list of 20 promises and actions from HM Government's sustainable development strategy 'One future : different paths : the UK’s shared framework for sustainable development'.Publisher ...
Sustainable Development Commission
core
Sustaining the planet by sustaining ourselves
BJC ReportsThe author transitions his career in oncology to one in planetary health. The career pivot begins after he recognizes similarities between the pandemic and the climate crisis. The author determines that stepping away from his role as chair of radiology for a one-year sabbatical is the most efficient way to learn about sustainability.
openaire +3 more sources