Results 151 to 160 of about 2,302,279 (319)

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

Vision for sustainable regeneration, environment & poverty : the missing link

open access: yes, 2012
This paper sets out our vision for sustainable regeneration, based on a review of existing literature, policy developments and initiatives.Publisher ...
Sustainable Development Commission
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Comments back from the Sustainable Communities Summit Workshop : creating communities with low environmental impact

open access: yes, 2012
Based on 'Report back from Sustainable Communities Summit Workshop : creating communities with a low environmental impact'.Publisher ...
Sustainable Development Commission
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

SDC submission to the DTI energy review : meeting the challenge : energy policy for the 21st century

open access: yes, 2012
Part of a series of documents submitted by the Sustainable Development Commission to inform 'The energy challenge : energy review report 2006'.Publisher ...
Sustainable Development Commission
core  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Wales natural environment framework consultation : Sustainable Development Commission feedback response

open access: yes, 2012
English language version of 'Ymgynghoriad ar fframwaith amgylchedd naturiol Cymru : ymateb i adborth Comisiwn Datblygu Cynaliadwy'.Evidence provided in response to the Welsh Assembly consultation entitled 'A living Wales : a new framework for our ...
Sustainable Development Commission Wales
core  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Are we measuring up to sustainable development?

open access: yes, 2012
Scotland is developing 'Choosing our future : Scotland's sustainable development strategy 'based on the UK 'The UK Government sustainable development strategy'.
Scotland. Scottish Executive   +4 more
core  

Home - About - Disclaimer - Privacy