Results 81 to 90 of about 3,112,864 (235)
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Leading by example? : not exactly… : SDC commentary on the Sustainable Development in Government Report 2005 [PDF]
, 2012 Sustainable Development Commission commentary on the 'Sustainable Development in Government Report 2005'.Publisher ...
Sustainable Development Commission
core +2 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
A Model for a Green, Lean Sustainable Improvement with Performance Measurement
Applied SciencesWith a turbulent market and a desire to withstand force, many companies lower the production price of their products using different approaches. On the one hand, they often use lean principles to reduce production costs, while they are compelled by the ...
Tomaž Berlec, Aljoša Peperko
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Malargüe Site Remediation: A Successful Solution for Uranium Mill Tailings
Yuanzineng kexue jishuComisión Nacional de Energía Atómica (CNEA) has the responsibility for restoring uranium mining facilities once the operations have finished. CNEA, within its Environmental Program and in compliance with its legal responsibilities, decides to implement a
BARARI E, DÍAZ J G, GIOMIA, KEMPF R A
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Sustainable communities policy review : Milton Keynes [PDF]
, 2012 This report is part of the evidence base for 'In-depth review of sustainable communities policy'.This paper collates evidence from an Sustainable Development Commission visit to Milton Keynes.Publisher ...
Sustainable Development Commission
core +2 more sources
Veterinary Evidence, 2019 PICO question In animals undergoing surgery, does the use of disposable synthetic drapes reduce the risk of surgical site infections when compared to reusable woven drapes?
Molly Vasanthakumar
doaj +1 more source