Results 121 to 130 of about 1,478,432 (305)
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Bryophytes as a Sustainable Alternative for Period Products
ProceedingsThroughout history, bryophytes have been utilized in various contexts for their remarkable properties [...]
Laura Roxana Horvath +3 more
doaj +1 more source
SUSTAINABLE TOURISM – A DYNAMICS METHOD FOR DESTINATION PLANNING Community approach: A case from south of Albania [PDF]
The main aim of this paper is directed in exploring alternative and sustainable tourism not only as one of the main sector of Albanian Economy, but as a planning tool from the community approach view. All the master plans, dynamics processes that involve
Dklodiana Gorica +2 more
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Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Sustainable inland transportation [PDF]
Inland navigation is often mentioned as a ‘green’ alternative for the two other main inland transport modes: rail and road transport. In order to investigate the opportunities for inland navigation we first analyze the competitive position of inland ...
Beijer, C. +2 more
core +2 more sources
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
A review of the utilisation of water hyacinth: alternative and sustainable control measures for a noxious weed [PDF]
, 2002 (8 page ...
Ekelemu, J.K. +3 more
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FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Socio-economic impacts of alternative GIN control practices. Project deliverable 11 (WP4) [PDF]
, 2018 This report is a deliverable (WP4) from the EU-funded PrOPara project. The PrOPara project aspires to i) assess existing knowledge from research, development and benchmarking studies on alternatives to parasite control on organic ruminant farms, ii ...
Moakes, Simon, Quiédeville, Sylvain
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