Results 61 to 70 of about 4,166,525 (285)

Impact of Thermal Mass, Window Performance, and Window–Wall Ratio on Indoor Thermal Dynamics in Public Buildings

Buildings
Thermal comfort in public buildings is crucial for occupant well-being and energy efficiency. This study employs TRNSYS software to simulate the effects of thermal mass, window performance, and window–wall ratio (WWR) on summer thermal comfort.
Ran Cheng, Nan Zhang, Wengan Zhang, Yinan Sun, Bing Yin, Weijun Gao   +5 more
doaj   +1 more source

Carving Sustainability into Architecture Knowledge Practice

, 2023
In the daily work of a software architect, knowledge is ubiquitous. In addition to technical expertise, architecture knowledge (AK) also requires practical experience in the representation, communication, and management of architectural decisions. However, there is a pressing need to also incorporate sustainability aspects, i.e., capturing decisions ...
Markus Funke, Patricia Lago
openaire   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

The right ingredients : Sustainable Development Commission Scotland response to the discussion on a national food policy for Scotland [PDF]

, 2012
Response of the Sustainable Development Commission Scotland to a consultation on national food policy for Scotland.Publisher ...
Sustainable Development Commission Scotland
core   +2 more sources

The impact of virtual images of coastal landscape features on stress recovery based on EEG

Scientific Reports
Understanding how coastal landscape features influence stress recovery can provide valuable insights for designing healthier urban environments. This study aims to evaluate the psychological and physiological restorative effects of four types of coastal ...
Jing Shi, Nan Zhang, Yinan Sun, Jinming Jiang, Haoyan Duan, Weijun Gao   +5 more
doaj   +1 more source

Spatial (in)justice shaping the home as a space of work

Buildings & Cities
Drawing on an extensive literature review, this study examines how injustices manifest in space and the role of space in engendering injustices when associated with working at home.
Dalia Milián Bernal, Jasmin Laitinen, Hannah Shevchenko, Oxana Ivanova, Sofie Pelsmakers, Essi Nisonen   +5 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Architectural sustainability: A new inspiration [PDF]

SAJ - Serbian Architectural Journal, 2016
Sustainable building, use of local materials, responsible use of soils, re-use, adaptability to climate, are all concepts that became worldwide part of the vocabulary of contemporary architectural design since the energy expenditure in the construction sector has proved to be of such magnitude to be unsustainable in the medium and long term.
openaire   +3 more sources

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source