Results 61 to 70 of about 4,416,693 (237)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

The impact of electric heating cape on local thermal sensation and thermal comfort of officers

Scientific Reports
This study focuses on evaluating the thermoregulatory performance of a graphene-based electric heating cape and determining its optimal temperature for use in cool indoor environments during winter.
Yuxi Wang, Meng Wei, Shangjie Lin, Wei Mao, Xi Meng   +4 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Impact of Thermal Mass, Window Performance, and Window–Wall Ratio on Indoor Thermal Dynamics in Public Buildings

Buildings
Thermal comfort in public buildings is crucial for occupant well-being and energy efficiency. This study employs TRNSYS software to simulate the effects of thermal mass, window performance, and window–wall ratio (WWR) on summer thermal comfort.
Ran Cheng, Nan Zhang, Wengan Zhang, Yinan Sun, Bing Yin, Weijun Gao   +5 more
doaj   +1 more source

Carving Sustainability into Architecture Knowledge Practice

, 2023
In the daily work of a software architect, knowledge is ubiquitous. In addition to technical expertise, architecture knowledge (AK) also requires practical experience in the representation, communication, and management of architectural decisions. However, there is a pressing need to also incorporate sustainability aspects, i.e., capturing decisions ...
Markus Funke, Patricia Lago
openaire   +2 more sources

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

The impact of virtual images of coastal landscape features on stress recovery based on EEG

Scientific Reports
Understanding how coastal landscape features influence stress recovery can provide valuable insights for designing healthier urban environments. This study aims to evaluate the psychological and physiological restorative effects of four types of coastal ...
Jing Shi, Nan Zhang, Yinan Sun, Jinming Jiang, Haoyan Duan, Weijun Gao   +5 more
doaj   +1 more source

What can functional transcranial Doppler ultrasonography reveal about the cerebral lateralization of writing

FEBS Letters, EarlyView.
Which brain hemisphere controls writing? This review synthesizes all five functional transcranial Doppler studies of writing (handwriting and typing) published to date in adults and children. Right‐handers show left‐hemispheric dominance for the linguistic component of writing (written word generation), whereas findings for left‐handers remain ...
Marietta Papadatou‐Pastou
wiley   +1 more source

Architecture, design and planning towards sustainable development: Regional approaches [PDF]

, 2019
The special issue Architecture, Design and Planning towards Sustainable Development: Regional Approaches, discusses how the shaping of the built environment may contribute to sustainability and resilience.
Skjerven, Astrid, Martins, Nuno
core   +1 more source

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

FEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim, Thi Thanh Mai Tran, Nakyung Kang, Min‐Woo Lee, Mihye Lee   +4 more
wiley   +1 more source