Results 61 to 70 of about 468,681 (298)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Achieving economic and environmental sustainability through optimum balance of costs [PDF]

open access: yes, 2011
Awareness and significance of sustainable development (SD) has been growing around the world for the last few decades. Sustainable construction is now considered a way for the construction industry to contribute to this larger effort. It is clear why the
Ekundayo, Damilola   +3 more
core  

Sustainable and Healthy Buildings [PDF]

open access: yesIndoor and Built Environment, 2010
Nowadays, awareness and understanding on health and well-being related to various built-environments has become a part of the responsibility of architectural designers and scientists. It was in this context that the Center for Sustainable Healthy Buildings (CSHeB) at Kyung Hee University has been nominated as an Engineering Research Center (ERC) of an ...
openaire   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

How to achieve sustainability : regulatory challenges [PDF]

open access: yes, 2005
The importance of designing sustainable buildings is gaining greater acceptance worldwide. Evidence of this is how regulators are incorporating sustainable design principles into building regulations and requirements.
Ambrose, Michael, Miller, Anne
core   +1 more source

The application of a Bayesian approach to assess the seismic vulnerability of historical centers [PDF]

open access: yes, 2016
The seismic vulnerability of historical centers at a territorial scale cannot be assessed performing detailed analysis which are usually adopted at the single building scale.
Campostrini, G. P.   +5 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Sensible heating and cooling of indoor building spaces by eliminating local in-room humidity condensation (and the related drain pans and drainage pathways) by using calibrated humidity in air-renewal fan coil systems, for healthier NZEB, ZEB and ZCB [PDF]

open access: yesE3S Web of Conferences
The transition towards Nearly Zero Energy Buildings (NZEB), Zero Energy Buildings (ZEB) and Zero Carbon Buildings (ZCB) requires rethinking conventional HVAC approaches to indoor thermal and hygrometric control.
Gandini Jacques
doaj   +1 more source

Urban planning in Cracow and location of sustainable office buildings [PDF]

open access: yes, 2016
Social, economic, and environmental benefits of sustainable buildings result in increasing demand and supply of green office space and governments adopt green buildings requirements as policy instruments.
Agnieszka, Telega, Małgorzata, Zieba
core   +1 more source

Towards Sustainable Building Design [PDF]

open access: yesDesign Principles and Practices: An International Journal—Annual Review, 2009
Work recently undertaken at the University of Strathclyde, Department of Architecture, is concerned with the articulation of a management system that might support sustainable design. Aligned with the international standard ISO 14001, a system has been piloted in housing development projects around Glasgow, and offers a supporting framework for the ...
openaire   +2 more sources

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