Results 261 to 270 of about 652,689 (344)

Inhibition of AMPKα Pathway by Podocyte GOLM1 Exacerbates Diabetic Nephrology in Mice

open access: yesAdvanced Science, EarlyView.
Podocyte Golgi membrane protein 1 interacts with epidermal growth factor receptor to inhibit peroxisome proliferator activated receptor γ, and then inactivates adenosine monophosphate activated protein kinase α pathway, which facilitates diabetes‐related inflammation, oxidative damage, apoptosis, and renal dysfunction.
Peng Xu   +14 more
wiley   +1 more source

Critical Design Strategy of Thermogalvanic Hydrogels for Low‐Grade Heat Harvesting

open access: yesAdvanced Science, EarlyView.
This review highlights thermogalvanic hydrogels for efficient low‐grade heat harvesting, with a focus on design strategies. Key aspects include recent advances, thermoelectrochemical conversion mechanisms, performance metrics, enhancement approaches, and current device applications.
Wentao Lin   +7 more
wiley   +1 more source

Overcoming the Damping–Elasticity Paradox via 3D‐Printed NiTiSn Nanocomposite

open access: yesAdvanced Science, EarlyView.
Here a 3D‐printed nanoeutectic alloy is designed to exhibit a record‐breaking combination of exceptional damping capacity (tanδ > 0.10) and elastic strain exceeding 4.5% at a high stress ≈1500 MPa, overcoming the damping‐elasticity paradox in high damping alloys.
Bo Feng   +13 more
wiley   +1 more source

Sustainable and Direct Upcycling of Waste Graphite Anodes via Deep Eutectic Solvents

open access: yesAdvanced Science, EarlyView.
A charged particle attacks the vacancy to realize the in‐situ P‐doping model. Cl− anions chelate with charged metal ions for the purpose of impurity removal, and meanwhile the cations bind to the electrons on the vacancy surface to neutralize the electrons.
Xue Liu   +8 more
wiley   +1 more source

Modulating Macrophage–Nucleus Pulposus Cell Crosstalk via Sequential Drug Delivery Attenuates Disc Degeneration

open access: yesAdvanced Science, EarlyView.
The G‐CS/MSN drug delivery system enhances intervertebral disc repair through sequential drug release. Abstract Intervertebral disc degeneration (IDD) is characterized by an inflammatory environment and dysregulation of the extracellular matrix metabolism (ECM).
Xiangzhen Kong   +12 more
wiley   +1 more source

ALKBH5‐Mediated M6A Demethylation of G3BP1 Attenuates Ferroptosis Via Cytoplasmic Retention of YBX1/p53 in Diabetic Myocardial Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
ALKBH5 promoted G3BP1 expression via m⁶A methylation at sites 142/173. G3BP1 interacts with YBX1 and p53, reducing their nuclear translocation and decreasing p53‐mediated SLC7A11 repression. This inhibites cardiomyocyte ferroptosis and mitigates myocardial damage during diabetic ischemia‐reperfusion injury.
Wenyuan Li   +5 more
wiley   +1 more source

Edible and Recyclable Gelatin‐Based Electronics for High‐Precision Health and Environmental Monitoring

open access: yesAdvanced Science, EarlyView.
An edible and recyclable composite film composed of gelatin and activated charcoal is presented for multifunctional health and environmental monitoring. The edible films exhibit tuneable mechanical and electrical properties, along with multimodal sensing capabilities for strain, humidity, and temperature. The composite film is degradable and recyclable,
Ming Dong   +6 more
wiley   +1 more source

A Self‐Powered Double U‐Finger MME Resonator Capable of Wirelessly Capturing Abnormal Message in Smart Grid Networks

open access: yesAdvanced Science, EarlyView.
This study presents a magneto‐mechano‐electric resonator that efficiently harvests energy and monitors grid safety in Power Internet of Things systems. The resonator, consisting of two U‐fingers with different resonant frequencies, captures stray magnetic field energy and detects fault messages. It produces high power for self‐powered and achieves high
Xinyi Zheng   +10 more
wiley   +1 more source

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