Results 201 to 210 of about 5,762,912 (277)

Telomere-to-telomere genome assemblies of male and female greater amberjack (Seriola dumerili). [PDF]

Sci Data
Duan B, Lv Y, Weng Z, Li Y, Zhang R, Chen J, Yang S, Wu J, Zhang K.   +8 more
europepmc   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

Gonadotropin‐Inhibitory Hormone (GnIH) and Its Receptor GPR147 Mediates Acute Stress‐Induced Activation of the Locus Coeruleus‐SAM Axis

Advanced Science, EarlyView.
ABSTRACT Gonadotropin‐inhibitory hormone (GnIH, also known as RFamide‐related peptide‐3, RFRP‐3) is a hypothalamic neuropeptide that regulates vertebrate reproduction via its receptor GPR147. Although GnIH is known to mediate stress‐induced reproductive suppression, its role in broader stress responses remains unclear.
Jiani Zhang, Hongyu Zhu, Wenqi Wang, Bingqian Shen, Yuanyuan Xin, Xingxing Song, Xuanyi Lu, Lixuan Li, Siting Chen, Xiaochen Zhang, Jialing Zeng, Haodong Zheng, Jianlong Lao, Ke Peng, Yixian Wei, Jiaming Zheng, Chuanhuo Hu, Xiaoye Wang, Xun Li   +18 more
wiley   +1 more source

Species identification, discovery, and biomonitoring: Strategic priorities for DNA barcoding in Europe, set in a global context. [PDF]

Bioscience
Hollingsworth PM, Fantoni K, Koureas D, Arakelyan M, Aravanopoulos FA, Bacela-Spychalska K, Ballesteros-Mejia L, Beja P, Bonchev GN, Bou Dagher Kharrat M, Bourlat SJ, Chkhartishvili T, Čiampor F, Costa FO, Csabai Z, Dankova G, Ekrem T, Emerson B, Ferreira S, Gadawski P, Gkagkavouzis K, Hebert PDN, Ichim MC, Jelić M, Kaitetzidou E, Kalamujić Stroil B, Kamenova S, Keskin E, Laini A, Lawniczak M, Madesis P, Montagna M, Mutanen M, Peters RS, Price B, Rewicz T, Rougerie R, Rulik B, Szucsich N, Vos R, Goodall-Copestake WP, Triantafyllidis A, Grabowski M.   +42 more
europepmc   +1 more source

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

Advanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu, Miaozhan Zou, Yunshang Bai, Yang He, Zhihao Jin, Baozhi Yang, Jinjin Du, Pei Ouyang, Yuanyuan Cai, Yuheng Zhang, Bingying Du, Chengcheng Ge, Jian‐an Gong, Xiaoyu Li, Yuanyi Zheng, Jing Ding, Bo Peng, Yanxia Rao   +17 more
wiley   +1 more source

Plant Viral Metagenomic Analysis from a Preliminary Field Survey in Angola Reveals Complex Mixed Infections in Vegetable Crops. [PDF]

Viruses
Amoia SS, Giampetruzzi A, Neto FFS, António LF, Pais da Cunha AT, Minafra A.   +5 more
europepmc   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

µCT scanning effects on aDNA and a multi-step workflow for archaeological petrous portions. [PDF]

PLoS One
Menéndez LP, Luisi P, López-Sosa MC, Da Silva SM, Buck LT, Kuzminsky SC, Sánchez MQ, Le Maître A, Chappard C, Rios C, Groh H, Siles W, Hernández GM, Becerra-Valdivia L, Argüelles JM, Yáñez B, de la Fuente Castro C, Tamburrini C, Garcia-Deister V, Contreras-Sieck MA, Pasqualini S, Novellino P, Acosta Morano C, Guevara D, Mansegosa D, Chiavazza H, Giannotti S, Tissera L, Pastor S, Díaz I, Grimoldi MS, Silva-Pinto V, Solari A, Pessis AM, Barberena R, Rascovan N.   +35 more
europepmc   +1 more source

Synthetic Toll‐Like Receptors for Control of Innate Immunity With Far‐Red Light

Advanced Science, EarlyView.
Synthetic Toll‐like receptors (TLRs) are engineered by replacing their natural sensing regions with a far‐red‐light‐responsive module from a bacterial phytochrome. These synthetic receptors enable light‐controlled regulation of immune signaling in mammalian cells.
Anna V. Leopold, Vladislav V. Verkhusha
wiley   +1 more source

Challenges and Opportunities for Theory-Grounded Data Visualization in Extended Reality. [PDF]

IEEE Comput Graph Appl
Bueckle A, Hutter CVR, Raidou RG, Bryan C, Mindek P, Kaufmann H, Elmqvist N, Menche J, Borner K, Rhyne TM.   +9 more
europepmc   +1 more source