Results 31 to 40 of about 5,762,912 (277)

Green Libraries As an Active Participant in Environmental Awareness and Ecological Action

open access: yesČitalište
In 2015, The United Nations launched the Sustainable Development Agenda 2030, which includes libraries as important contributors to developing nature preservation strategies and enabling the progress of humanity.
Gordana Stojanović   +2 more
doaj   +1 more source

Sustainability 3.0 in Libraries: A Challenge for Management

open access: yesPublications, 2022
This article works on the three questions: “How can libraries make an effective contribution to resolving the sustainability challenges we are collectively facing?”; “When are libraries truly sustainable?”; and “How can library management support this shift?”.
openaire   +3 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Sustainable development in government 2008 : challenges for government [PDF]

open access: yes, 2012
Our seventh annual SDiG assessment found good overall progress by the UK Government, especially on targets for water, waste and travel, though reductions in carbon emissions from offices were still not on track.Publisher ...
Sustainable Development Commission
core   +2 more sources

The Role of Canadian Public Libraries in Facilitating Sustainable Lifestyles

open access: yesPartnership: The Canadian Journal of Library and Information Practice and Research
The importance of sustainable lifestyles is addressed in two of the United Nation’s Sustainable Development Goals. Public libraries can play a significant role in providing information and resources to lead to positive behavioural actions to help ...
Louise Spiteri
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Sustainability and Academic Libraries. A story from Denmark

open access: yesLiber Quarterly: The Journal of European Research Libraries
The University of Southern Denmark has set out its Vision and Strategy and the Library has become an eminent partner in supporting the University in achieving its sustainability ambitions.
Najmeh Shaghaei, Dorch Bertil
doaj   +1 more source

Steppingstones to More Sustainable Public Libraries in Finland

open access: yesInternational Journal of Librarianship, 2020
Public libraries in Finland have a strong history of cooperating and networking. Implementing SDGs and steering the action toward sustainability, however, has been so far carried out mainly out by individual libraries.
Ulla Pötsönen   +2 more
doaj   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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