Results 101 to 110 of about 6,076,403 (347)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

From accelerometer data to activity patterns in chronic pain: methodical reasoning is key

Frontiers in Sports and Active Living
Activity pattern (AP) concepts are widely used in interdisciplinary chronic pain (CP) care. It is assumed that AP can be objectively measured with accelerometry, but previous results show inconsistencies which may be attributed to methodical choices ...
Annet Doomen, Annet Doomen, Ivan Huijnen, Ivan Huijnen, Ivan Huijnen, Harriët Wittink, Tale Evenhuis, Martine Verwoerd, Rob Smeets, Rob Smeets, Rob Smeets   +10 more
doaj   +1 more source

Transitions on the home front: A story of sustainable living beyond eco-efficiency

, 2017
The environmental impact associated with modern ways of living is widely recognized and has been increasingly problematized. A prevailing discourse in sustainable housing tends to focus on building performance, along with compelling stories of “green ...
Pernilla Hagbert, K. Bradley
semanticscholar   +1 more source

Cultures within a culture: the role of nationality and religion for environmentally significant behaviour in students living in university accommodation [PDF]

, 2011
Reducing global warming cannot be achieved through technological interventions alone; it requires a change in human behaviour. Households are a major contributor to carbon emissions, and thus play an integral part in strategies aiming at a more ...
Cooper, J., Huebner, G.M., Jones, K.
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Games to support teaching clinical reasoning in health professions education: a scoping review

Medical Education Online
Introduction Given the complexity of teaching clinical reasoning to (future) healthcare professionals, the utilization of serious games has become popular for supporting clinical reasoning education. This scoping review outlines games designed to support
Gilbert Koelewijn, Marije P. Hennus, Helianthe S. M. Kort, Joost Frenkel, Thijs van Houwelingen   +4 more
doaj   +1 more source

An Indicator-Based Approach for Analysing the Resilience of Transitions for Energy Regions. Part II: Empirical Application to the Case of Weiz-Gleisdorf, Austria

Energies, 2018
In this paper, we apply an indicator-based approach to measure the resilience of energy regions in transition to a case study region in Austria. The indicator-based approach allows to determine the resilience of the transition of regional energy systems ...
Romano Wyss, Susan Mühlemeier, Claudia R. Binder   +2 more
doaj   +1 more source

Sustainable Agriculture in Rural Central American Countries: Grassroots Effectiveness in Initiating Cultural Change [PDF]

, 2012
This study examines grassroots organizations with respect to their effectiveness in initiating a cultural change in the agricultural practices in Central American countries.
Field, Zach
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source