Results 31 to 40 of about 3,068,202 (243)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Study of the Impact of E-Machine in Hybrid Dual Clutch Transmission Powertrain

Energies, 2022
Recent studies show that hybrid powertrains with dual clutch transmission are becoming more common. This is mainly influenced by the fact that they have higher efficiency, allow power-on shifting, and are more compact.
Irfan Khan, Sanjarbek Ruzimov, Nicola Amati, Andrea Tonoli   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

ShipNetSim: An Open-Source Simulator for Real-Time Energy Consumption and Emission Analysis in Large-Scale Maritime Networks

Journal of Marine Science and Engineering
The imperative of decarbonization in maritime shipping is underscored by the sector’s sizeable contribution to worldwide greenhouse gas emissions.
Ahmed Aredah, Hesham A. Rakha
doaj   +1 more source

SUSTAINABLE URBAN MOBILITY: EU POLICY SOLUTIONS AND PRACTICES [PDF]

, 2022
openL’obiettivo della tesi è di dimostrare che l’Unione Europea sta attuando una transizione verso una politica di trasporti più sostenibile e nel farlo, sta adottando uno strumento di soft-policy innovativo denominato Sustainable Urban Mobility Plan ...
GIRO, GAIA
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Brake particle emissions: Effect of temperature and modeling of temperature behavior

Results in Engineering
Reducing the non-exhaust particle emissions has become the new challenge to pursue a more sustainable transport system. Understanding the characteristics of brake wear particles and the factors affecting their formation is essential for developing ...
Francesco Catapano, Silvana Di Iorio, Agnese Magno, Luigi Sequino, Bianca Maria Vaglieco   +4 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Gweithredu’n gallach : sut y gall technoleg gwybodaeth a chyfathrebu hyrwyddo symudedd cynaliadw

, 2012
Welsh language version of 'Smarter moves : how information communications technology can promote sustainable mobility'.Transport currently accounts for 29% of the UK’s total carbon dioxide emissions, and unlike other major sectors, its emissions continue
Sustainable Development Commission Wales
core   +2 more sources

Enhanced Quasi-One-Dimensional Modeling and Design Performance Assessment of an ORC with Radial Turbine for Waste Heat Recovery

Energies
Organic Rankine Cycles (ORCs) are widely recognized as an effective solution for waste heat recovery (WHR). However, the design and optimization of these systems must address the tradeoff between computational efficiency and the need to capture complex ...
Raffaele Carandente, Alessandro di Gaeta, Veniero Giglio, Fabrizio Reale   +3 more
doaj   +1 more source