Results 101 to 110 of about 212,772 (313)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Artificial intelligence-driven green innovation in packaging: A systematic review of adoption and diffusion challenges

open access: yesIntelligent Systems with Applications
Global concern about environmental protection has intensified the demand for sustainable packaging solutions. Integrating artificial intelligence (AI) into green innovation offers a transformative way to address these challenges.
Ye Ma   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Environmental Benchmarking of Suppliers in the UK Food Sector [PDF]

open access: yes, 2012
This paper aims to develop an audit toolkit that enables companies in the food sector to benchmark their suppliers in terms of environmental management.
Cifuentes, Marta Salvà, Jones, Simon
core  

Imagining Corporate Sustainability as a Public Good Rather than a Corporate Bad [PDF]

open access: yes, 2014
Corporations have been criticized for their environmental misdeeds for over a century, so it is not surprising that many view corporate approaches to sustainability with skepticism.
Wagner, Wendy E.
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

The Largest Environmental Movement: Recycling and Consumption Work in Sweden [PDF]

open access: yes, 2013
By sorting their waste for recycling, Swedes are told that they are part of 'Sweden's largest environmental movement' (Avfall Sverige, 2008). Recycling in Sweden is understood as an environmental action by all parties within society (including consumers,
Wheeler, Kathryn
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

A Decision Framework for Selecting Highly Sustainable Packaging Circular Model in Mass-Customized Packaging Industry

open access: yesApplied Sciences
The selection of a sustainable packaging circular model approach entails numerous obstacles under rapidly developing circumstances, such as environmental factors, market competition, and advancing technology, impacting decision-making processes.
Ravishankar Rajendran   +1 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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