Results 41 to 50 of about 13,263 (265)

FUCA2 Sustains AKT Signaling and Suppresses Senescence by Antagonizing FUT3‐Mediated ErbB3 Fucosylation in Lung Adenocarcinoma

Advanced Science, EarlyView.
ABSTRACT While targeted therapies have improved outcomes in lung adenocarcinoma (LUAD), many patients still lack targetable mutations. Here, we identified alpha‐L‐fucosidase 2 (FUCA2) as a crucial driver of LUAD by preventing cellular senescence. Mechanistically, through the restriction of fucosyltransferase 3 (FUT3)‐mediated α‐1,3‐fucosylation of ...
Lu Chen, Jintao Guo, Fei Li, Mingjie Gao, Runyang Li, Zhaozhang Huang, Yaolin Zheng, Chunyi Gao, Jihuan Hou, Qiang Yu, Bowen Zheng, Xuemei Chen, Wenqing Zhang, Xiaoting Hong, Yali Zheng, Daxuan Wang, Qiyuan Li, Tianhui Hu, Yan‐yan Zhan   +18 more
wiley   +1 more source

Leveraging AI for sustainable public procurement: opportunities and challenges

Frontiers in Sustainability
Even though sustainable public procurement is critical to achieving global climate goals, most public organizations struggle to implement it. While artificial intelligence holds promise for addressing these challenges, its use in the public sector ...
Marta Andhov, Marta Andhov, Nicole Darnall, Alexandra Andhov, Alexandra Andhov   +4 more
doaj   +1 more source

De la Responsabilité sociale des organisations à l’achat public responsable : entre contraintes et performances. Compte rendu de journée d’étude

Développement Durable et Territoires, 2019
Responsible public procurement can be understood as a new conception of public procurement, which could reaffirm the role of public actors in the institutionalization of sustainable development, especially on a territorial scale.
Olivier Gayot
doaj   +1 more source

Chitosan‐Carbon Dot Composite Materials Form a Leaf Surface Barrier to Mitigate the Enrichment and Invasion of Nanoplastics: From Leaf Interface to Systemic Response

Advanced Science, EarlyView.
Foliar spraying of CS‐CDs can form a film on the leaves of Brassica rapa, effectively reducing the enrichment and absorption of PS in the leaves, while increasing the biomass and nutrient content of the plants. In addition, CS‐CDs can also enrich the interfoliar microbial community and activate the plant's own defense metabolic pathways.
Beibei Zhao, Mei Li, Mengjiao Fan, Chuanhuan Liu, Jie Jiang, Jia Song, Yingzhu Liu   +6 more
wiley   +1 more source

Public procurement for sustainability

Public procurement emerges as an instrument to promote sustainability and innovation, facilitating the implementation of policy goals. Adaptive procurement leverages sustainable innovation available in the market. Developmental procurement creates demand for solutions that do not exist yet but need to be developed first.
Pihlajamaa Matti, Valovirta Ville
openaire   +1 more source

Analysing the drivers for sustainable public procurement

Environment Systems and Decisions
AbstractSustainable public procurement (SPP) is aimed at using government purchasing power to foster sustainable production and consumption and develop more sustainable business models. The implementation of SPP has been undertaken through several disciplinary approaches, including practical and research efforts based on organisational change ...
Felippe Santos, Rodrigo Lozano, Maria Barreiro-Gen   +2 more
openaire   +4 more sources

PIEZO1 is Required for Acute Myeloid Leukemia Progression and Leukemia Stem Cell Maintenance via HIF1A‐SLC7A11 Axis‐Mediated Ferroptosis Defense

Advanced Science, EarlyView.
This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang, Ziyan Cao, Kexin Gao, Shuxin Yao, Yanbing Zheng, Manman Cui, Rong Yin, Guoqiang Han, Jin Hu, Chengyi Wang, Haojian Zhang   +10 more
wiley   +1 more source

ENHANCING THE LEGAL FRAMEWORK FOR SUSTAINABLE PUBLIC PROCUREMENT: A COMPREHENSIVE SUSTAINABLE DEVELOPMENT PLAN FOR INDONESIA

UUM Journal of Legal Studies
The concept of “sustainable public procurement” has emerged worldwide. It instructs governments to prioritize sustainability throughout the procurement process in the economic, social, and environmental aspects.
Rizky Amalia, Faizal Kurniawan, Hilda Yunita Sabrie, Wilda Prihatiningtyas, Yosua Putra Iskandar   +4 more
doaj   +1 more source

Implementation of sustainable public procurement in China: An assessment using quantitative text analysis in large-scale tender documents

Frontiers in Environmental Science, 2022
In recent years, increasing attention has been paid worldwide to the sustainable development of the economy and society. Because of its size and prevalence, public procurement has always been a powerful policy tool used to tackle issues related to the ...
Fuguo Cao, Fuguo Cao, Runyu Li, Runyu Li, Xiaoyan Cao, Xiaoyan Cao   +5 more
doaj   +1 more source

Supercritical CO2‐Induced Porous MXene Films for Electromagnetic Interference Shielding and Infrared Stealth

Advanced Science, EarlyView.
The phase transition of supercritical CO2 induces the foaming of dense MXene film without compromise inherent structure of MXene nanosheet. The foamed porous MXene film manifests remarkable EMI shielding and infrared thermal camouflage performances. Moreover, the foaming strategy is broadly adaptable and can be extended to other two‐dimensional films ...
Hui Zhao, Shuai Li, Jiabei He, Tong Gao, Jingfeng Wang, Dongxiao Kan, Wangtu Huo, Lixin Chen   +7 more
wiley   +1 more source