Results 61 to 70 of about 14,107,306 (299)

Restores Aβ Clearance by Overcoming PCSK9–LRP1 Dysregulation and TRIB3‐Mediated Autophagy Blockade in Alzheimer's Disease

Advanced Science, EarlyView.
PCSK9 upregulation in cerebrovascular endothelial cells and microglia destabilizes the Aβ transporter LRP1, while TRIB3‐associated autophagy blockade further limits intracellular Aβ degradation. A RAP‐modified tea‐polyphenol nanoparticle co‐delivers siPCSK9 and siTRIB3 to restore LRP1‐mediated Aβ efflux and autophagy‐dependent degradation, reducing Aβ ...
Jie Miao, Jing Wang, Yankun Li, Haipei Zhang, Yanli Zhang, Qingnian Li, Bo Xiao, Wenhu Zhou, Junhong Guo   +8 more
wiley   +1 more source

In Situ CO2‐Induced Hydrogels for Enhancing Carbon Sequestration in Saline Aquifers

Advanced Science, EarlyView.
A novel integrated method that combines in situ CO2‐induced phase‐transition hydrogels formed by a C22‐tailed tertiary amine dispersion with tailored deep eutectic solvents to increase CO2 sequestration in saline aquifers. ABSTRACT Carbon sequestration in saline aquifers underpins global net‑zero emission goals, yet existing CO2 storage capacity ...
Fuchuan Liu, Xinjie Luo, Dianguo Wu, Xuezhi Zhao, Yan Zhang, Yujun Feng   +5 more
wiley   +1 more source

‘Europe 2020’ and the EU Public Procurement and State Aid Rules: Good Intentions That Pave a Road to Hell?

Croatian Yearbook of European Law and Policy, 2016
In 2010, the European Union launched ‘Europe 2020, a strategy for smart, sustainable and inclusive growth’ whose goals in employment, innovation, education, social inclusion and climate/energy need to be reached by 2020.
Stefan Martinić, Ana Kozina
doaj   +1 more source

Targeting Macrophage‐Mediated Lymphatic Immunosuppression to Prevent Tumor Recurrence After Microwave Ablation

Advanced Science, EarlyView.
Incomplete microwave ablation induces animmunosuppressive microenvironment in tumor‐draining lymph nodes. An albumin‐based lipoprotein nanosystem enables coordinated delivery of immunomodulators to tumor‐draining lymph nodes and residual tumors, reverses post‐ablation immunosuppression, suppresses residual tumor growth, and promotes durable antitumor ...
Xuexia Shan, Yuting Shen, Xiaodong Hou, Fengshan Jin, Shaoyue Li, Weichen Xu, Weiwei Ren, Xiaowan Bo, Qiuyan Li, Shuo Liu, Weifan Hao, Chengzhong Peng, Huixiong Xu, Liping Sun, Wenwen Yue   +14 more
wiley   +1 more source

The Role of Local Contracting Authorities in Green Purchasing of Paper Products

EU agrarian Law, 2019
Green Public Procurement is currently a voluntary instrument to promote Sustainable Consumption and Production and Sustainable Industrial Policy. Surveys in this field help to understand how individual States, Public Authorities and Organizations, are ...
Malatinec Tomáš, Kyjovský Ján
doaj   +1 more source

An Adenoviral‐Vectored Tp0326 Vaccine Elicits Robust Functional Antibodies to Prevent Treponema pallidum Dissemination in a Rabbit Model

Advanced Science, EarlyView.
Vaccination promotes cellular infiltration into primary lesions and effectively inhibits T. pallidum dissemination to distal organs. Notably, transfer of lesion tissue from immunized animals fails to establish infection in naive recipients, confirming specific protective immunity.
Yinbo Jiang, Xinyuan Li, Lixia Huang, Xiangcai Zhang, Wujian Ke   +4 more
wiley   +1 more source

Green Public Procurement: Case Study of Latvian Municipalities

Economics and Business, 2019
Green public procurement (GPP) is an instrument for public institutions that have made sustainable consumption and financial aids savings, particularly taking into consideration expenses of the total life cycle of the agreement, not just the procurement ...
Pelša Inese
doaj   +1 more source

Sustainable Procurement: Literature Review: Report #1

, 2020
Our community has increasing expectations of government and private industry to support sustainable products and practices. There is also great interest shown by industry to reduce waste and emissions, and improve social outcomes.
Bevan, Whitney (R19816), Shou, Wenchi (R19820), Caldera, Savindi, Mohamed, Sherif A., Zhang, Peng (R19643), Le, Tiendung, Feng, Yingbin (R16766)   +6 more
core  

Sustainable public procurement best practices at sub-national level: drivers of strategic public procurement practices in Catalonia and Barcelona

, 2020
The strategic use of public procurement across the European Union to contribute to sustainable development has been underdeveloped and unequally distributed among the EU Member States, with seven Member States being sustainable public procurement leaders,
Mélon, Lela
core   +1 more source

Mechanical Distraction Engages a Neuro‐Immune Program to Drive Regenerative Soft‐Tissue Healing in Ilizarov Bone Transport

Advanced Science, EarlyView.
Ilizarov bone transport accelerates healing of soft‐tissue wounds through unclear mechanisms. In a rat model, sustained mechanical distraction elicits calcitonin gene‐related peptide (CGRP)‐dominant sensory reinnervation, creating a niche that shifts immune cells from inflammatory to repair‐promoting states and speeds re‐epithelialization.
Yueliang Zhu, Jiayu Chen, Xuehuan Wen, Kaijia Tang, Ling Gao, Chenxing Wang, Yixuan Feng, Si‐He Qin, Tao Chen, Xiaohua Yu   +9 more
wiley   +1 more source