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An antioxidant and antibacterial octyl gallate sustained-release ointment for periodontitis treatment. [PDF]
Wang HP +5 more
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Sustained-release oxymatrine hydrogel enhances the survival of transplanted placental mesenchymal stem cells and promotes wound healing in diabetic mice. [PDF]
Liu L +5 more
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Environment-Responsive Sustained-Release Nanoparticles for the Protection, Delivery and Release of Clove Essential Oil to Improve Foodborne Bacterial Colitis Treatment. [PDF]
Bai J +7 more
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Indomethacin Sustained-Release?
Drug Intelligence & Clinical Pharmacy, 1984Recently, many new formulations of older drugs have been marketed as sustained-release preparations. Only some of these compounds have scientific rationale supporting their development. At least two inherent properties of a drug are desirable in considering its reformulation into a sustained-release entity.
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Sustained-Release Butorphanol Microparticles
Drug Development and Industrial Pharmacy, 2000Various butorphanol-loaded microparticles have been prepared with a biodegradable copolymer P(FAD-SA) of erucic acid dimer (FAD) and sebacic acid (SA) and a copolymer P(CPP-SA) of carboxyphenoxypropane (CPP) and SA using a melt compounding and milling method. Drug release was measured in vitro following incubation of drug-loaded microparticles in water
H C, Chang, L C, Li
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Sustained release hormonal preparations
Journal of Steroid Biochemistry, 1970ABSTRACT Determination of radioactivity in urine, faeces and various organs in rats was used to monitor the absorption of labelled 6-methyl-17α-acetoxy-4,6-pregnadiene-3,20-dione from polydimethylsiloxane implants or after oral administration. Given orally, peak plasma levels were obtained 4 h after administration. It took about 4 days to reach
Fred A. Kincl +3 more
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Pharmacokinetics of sustained-release etodolac
Rheumatology International, 1993Etodolac exhibits linear pharmacokinetics, good oral bioavailability, greater than 99% protein binding, a low oral clearance (almost exclusively non-renal), a relatively small volume of distribution and a half-life that averages 7.3 +/- 4.0 h. No significant pharmacokinetic differences have been noted in patients with mild to moderate renal impairment,
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Tramadol Sustained-Release Capsules
Drugs, 2006Tramadol is a synthetic, centrally acting analgesic. A sustained-release (SR) capsule formulation of tramadol gradually releases active drug, allowing for twice-daily dosing. Compared with tramadol SR tablets, tramadol SR capsules produced a smoother plasma concentration profile, with more gradual absorption and lower peak concentrations.
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Oral Sustained-Release Medications
AJN, American Journal of Nursing, 1963F OR MANY YEARS, there has been an active interest in modifying oral preparations of drugs to delay and prolong their absorption from the gastrointestinal tract so that a sustained action might be obtained. About 10 years have passed since the first long-acting dosage form for oral use was introduced(1).
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