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Extending our confidence in sustained virological response
Liver International, 2016See Article on Page ...
Maan, Raoel, van der Meer, Adriaan
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Hepatitis C reinfection after sustained virological response
Journal of Hepatology, 2016On-going risk behaviour can lead to hepatitis C virus (HCV) reinfection following successful treatment. We aimed to assess the incidence of persistent HCV reinfection in a population of people who inject drugs (PWID) who had achieved sustained virological response (SVR) seven years earlier.In 2004-2006 we conducted a multicentre treatment trial ...
Håvard, Midgard +14 more
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Journal of Gastroenterology and Hepatology, 2007
AbstractBackground and Aim: The therapeutic effect of pegylated interferon (peg‐IFN)‐α‐2a combination with ribavirin on patients with chronic hepatitis C virus (HCV) infection is dependent on the rapidity of the virological response. The aim of this study was to investigate the predictive value of rapid virological response (RVR) and early virological
Jian-Wu, Yu +4 more
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AbstractBackground and Aim: The therapeutic effect of pegylated interferon (peg‐IFN)‐α‐2a combination with ribavirin on patients with chronic hepatitis C virus (HCV) infection is dependent on the rapidity of the virological response. The aim of this study was to investigate the predictive value of rapid virological response (RVR) and early virological
Jian-Wu, Yu +4 more
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Journal of Gastroenterology and Hepatology, 2010
AbstractBackground and Aim: A number of hepatitis C virus (HCV) patients without a rapid virological response (RVR) achieved a sustained virological response (SVR) with peginterferon‐α‐2a/ribavirin. The aim of this study was to identify factors associated with SVR in non‐RVR patients.Methods: Baseline and on‐treatment factors were used to explore the
Chung-Feng, Huang +13 more
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AbstractBackground and Aim: A number of hepatitis C virus (HCV) patients without a rapid virological response (RVR) achieved a sustained virological response (SVR) with peginterferon‐α‐2a/ribavirin. The aim of this study was to identify factors associated with SVR in non‐RVR patients.Methods: Baseline and on‐treatment factors were used to explore the
Chung-Feng, Huang +13 more
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Gastroenterology, 2010
G A A b st ra ct s to 4. Prior constitutional symptoms were present in 14%, and 38% were asymptomatic. Acute icteric feature was seen in 47%. Twelve patients had cirrhosis and were transplanted (57%). One had spontaneous remission and 1 died of liver failure.
Matthew J. Moeller +2 more
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G A A b st ra ct s to 4. Prior constitutional symptoms were present in 14%, and 38% were asymptomatic. Acute icteric feature was seen in 47%. Twelve patients had cirrhosis and were transplanted (57%). One had spontaneous remission and 1 died of liver failure.
Matthew J. Moeller +2 more
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Sustained Virological Response to Treatment in Patients With Chronic Hepatitis C
JAMA, 2013Mr Maisonneuve and Dr Bruno raise the possibility that the association between SVR and reduced occurrence of hepatocellular carcinoma among patients with chronic HCV infection and advanced hepatic fibrosis in our analyses could be confounded by HCV genotype or subtype.
Patrick, Maisonneuve, Savino, Bruno
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Augmentation of hepatitis C virus‐specific immunity and sustained virologic response
Journal of Viral Hepatitis, 2017SummaryTreatment for chronic hepatitis C virus (HCV) infection has rapidly evolved into interferon‐free directly acting antiviral regimens (DAA) that result in high sustained virologic response. DAAs primarily work by suppressing HCV replication and rely less on the immune system than interferon‐based therapies.
S. Shrivastava +6 more
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Sustained Virological Response After Early Discontinuation of Hepatitis C Treatment
Journal of Viral HepatitisABSTRACTTo date, the effectiveness of direct‐acting antivirals (DAAs) discontinued before 4 weeks has not been analysed in routine clinical practice. The study aimed to determine whether such a short therapy will enable achieving a sustained virological response under real‐world experience.
Robert Flisiak +13 more
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Telaprevir: Looking for a sustained virologic response in hepatitis C virus infection
Drugs of Today, 2011Telaprevir, a hepatitis C virus (HCV) NS3/NS4A protease inhibitor, was recently approved by the U.S. Food and Drug Administration for the treatment of chronic HCV genotype 1 infection. When given in combination with pegylated interferon and ribavirin, it demonstrated improved efficacy over conventional pegylated interferon and ribavirin therapy ...
V, Nehra +3 more
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Journal of Viral Hepatitis, 2010
Summary. Previous reports suggest cryoglobulinemia might influence the hepatitis C virus (HCV) infection clinical course and treatment response but this association has not been thoroughly evaluated. We aimed to assess the relationship between cryoglobulinemia and sustained viral response (SVR) in patients treated for HCV infection.
A G, Vigani +7 more
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Summary. Previous reports suggest cryoglobulinemia might influence the hepatitis C virus (HCV) infection clinical course and treatment response but this association has not been thoroughly evaluated. We aimed to assess the relationship between cryoglobulinemia and sustained viral response (SVR) in patients treated for HCV infection.
A G, Vigani +7 more
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