Results 31 to 40 of about 5,500,616 (251)

Real-World Single-Center Experience with Sofosbuvir-Based Regimens for the Treatment of Chronic Hepatitis C Genotype 1 Patients

Gut and Liver, 2017
Background/AimsThe approval of sofosbuvir (SOF), a direct-acting antiviral, has revolutionized the treatment of chronic hepatitis C virus (HCV).Methods : We assessed the sustained virological response (SVR) of SOF-based regimens in a real-world single ...
Hyun Phil Shin, Blaire Burman, Richard A. Kozarek, Amy Zeigler, Chia Wang, Houghton Lee, Troy Zehr, Alicia M. Edwards, Asma Siddique   +8 more
doaj   +1 more source

Myxovirus resistance, osteopontin and suppressor of cytokine signaling 3 polymorphisms predict hepatitis C virus therapy response in an admixed patient population: comparison with IL28B

Clinics, 2013
OBJECTIVES: Suppressor of cytokine signaling 3, myxovirus resistance protein and osteopontin gene polymorphisms may influence the therapeutic response in patients with chronic hepatitis C, and an association with IL28 might increase the power to predict ...
Ana Luiza Dias Angelo, Lourianne Nascimento Cavalcante, Kiyoko Abe-Sandes, Taisa Bonfim Machado, Denise Carneiro Lemaire, Fernanda Malta, Joao Renato Pinho, Luiz Guilherme Costa Lyra, Andre Castro Lyra   +8 more
doaj   +1 more source

Epidemiological characteristics and real‐world treatment outcomes of hepatitis C among HIV/HCV co‐infected patients in Myanmar: A prospective cohort study

Health Science Reports, 2023
Background and Aims In Myanmar, public sector treatment programs for hepatitis C virus (HCV) infection were nonexistent until June 2017. WHO highlights the importance of simplification of HCV service delivery through task‐shifting among health workers ...
Thein Min Swe, Derek. C. Johnson, Htay Thet Mar, Phone Thit, Tobias Homan, Cherry May Chu, Phyu Ei Mon, Thin Thin Thwe, Kyi Pyar Soe, Win Le Shwe Sin Ei, Nyan Lynn Tun, Kyaw Zay Lwin, Hayk Karakozian, Khin Sanda Aung, Aude Nguyen, Iza Ciglenecki, Natalia Tamayo, Anne Loarec   +17 more
doaj   +1 more source

Association of IFNL3 rs12979860 and rs8099917 with biochemical predictors of interferon responsiveness in chronic hepatitis C virus infection [PDF]

, 2013
Background & Aims: Genetic variations near the interferon lambda 3 gene (IFNL3, IL28B) are the most powerful predictors for sustained virologic response (SVR) in patients with chronic hepatitis C virus (HCV) infection, compared to other biochemical or ...
Simone Susser (48294), Annika Brodzinski, Thomas Berg (186372), Migaud, Pascal, Jacob George (205614), Brodzinski, Annika, Tobias Müller, Susser, Simone, Stephan Böhm (334611), Sarrazin, Christoph, Christoph Sarrazin (48298), Pascal Migaud, Schott, Eckart, Bömmel, Florian van, Heiko Witt, Florian van Bömmel, Janett Fischer, Christoph Sarrazin, Stewart, Graeme, Graeme Stewart, Witt, Heiko, Thomas Berg, Simone Susser, Balazs Fülöp, Fülöp, Balazs, Stephan Böhm, Annika Brodzinski (477753), Balazs Fülöp (477754), Müller, Tobias, Fischer, Janett, Böhm, Stephan, Berg, Thomas, Tobias Müller (163591), Janett Fischer (477751), Eckart Schott (320945), Graeme Stewart (208243), Jacob George, Heiko Witt (161481), Pascal Migaud (477752), George, Jacob, Eckart Schott, Florian van Bömmel (477755)   +41 more
core   +1 more source

Meta‐analysis: insulin resistance and sustained virological response in hepatitis C [PDF]

Alimentary Pharmacology & Therapeutics, 2011
Aliment Pharmacol Ther 2011; 34: 297–305SummaryBackground  A higher baseline homeostasis model assessment of insulin resistance (HOMA‐IR) score has sometimes predicted a poorer sustained virological response (SVR) rate to peginterferon/ribavirin therapy in treatment‐naïve chronic hepatitis C patients.Aim  To perform a meta‐analysis to evaluate the ...
Eslam, Mohammed, Aparcero, Reyes, Kawaguchi, Takumi, del Campo, José A., Sata, Michio, Khattab, Mahmoud A, Romero-Gomez, Manuel   +6 more
openaire   +2 more sources

Efficacy of Sofosbuvir and Daclatasvir in Achieving the End Treatment Response and Sustained Viral Response in Patients infected with Hepatitis C Virus Genotype 3

Pakistan Armed Forces Medical Journal, 2022
Objective: To ascertain the efficacy of sofosbuvir combined with daclatasvir against hepatitis C genotype 3 infection. Study Design: Prospective longitudinal study.
Zabih Ullah, Sultan Zeb Khan, Hassam Lodhi, Hafizullah Khan, Rania Hidayat, Moiz Ahmed   +5 more
doaj   +1 more source

Hepatitis C Prevalence and Responses to Pegylated Interferon + Ribavirin Treatment Among Prisoners

Viral Hepatitis Journal, 2017
Objective: The aim of our study was to identify the hepatitis C prevalence in prisoners and to share experiences of pegylated interferon (peg-IFN) + ribavirin (RBV) treatment.
Hasan Selçuk ÖZGER, Ömer KARAŞAHİN, Mehmet Armağan TOY, Sibel İBA YILMAZ, Kenan HIZEL   +4 more
doaj   +1 more source

Development and surveillance of hepatocellular carcinoma in patients with sustained virologic response after antiviral therapy for chronic hepatitis C [PDF]

Clinical and Molecular Hepatology, 2019
Hepatitis C virus (HCV) infection is a major risk factor for liver cirrhosis and hepatocellular carcinoma (HCC), and is a leading cause of liver-related deaths worldwide. Recently available direct-acting antiviral agent is very safe and highly effective (
Seong Kyun Na, Byung-Cheol Song
doaj   +1 more source

Real-Life Effectiveness and Safety of Glecaprevir/Pibrentasvir for Korean Patients with Chronic Hepatitis C at a Single Institution

Gut and Liver, 2021
Background/Aims: Glecaprevir/pibrentasvir (G/P) is a combination of direct-acting antiviral agents that is an approved treatment for chronic infections by all six hepatitis C virus (HCV) genotypes.
Young Joo Park, Hyun Young Woo, Jeong Heo, Sang Gyu Park, Young Mi Hong, Ki Tae Yoon, Dong Uk Kim, Gwang Ha Kim, Hyung Hoi Kim, Geun Am Song, Mong Cho   +10 more
doaj   +1 more source

Declining sustained virological response in hepatitis C.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2007
To determine the response of treatment with standard interferon and Ribazole in treatment naïve hepatitis C infected patients, with different grades of activity.A quasi-experimental study.This study was carried out at the Department of Medicine, KRL General Hospital, Islamabad, from January 2001 to September 2004.A total of 300 patients were enrolled ...
Uzma, Batool, Saleem, Qureshi
openaire   +2 more sources